(4 references)-
- 抗原 See all Integrin beta 4 (ITGB4) 抗体
- Integrin beta 4 (ITGB4)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Integrin beta 4 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with CD104, integrin β4 chain, a 205 kDa transmembrane glycoprotein which associates with CD49f (integrin α6 chain) to form the α6/β4 (CD49f/CD104) complex. CD104 is expressed on epithelial cells, Schwann cells, and some tumor cells. The CD49f/CD104 complex is located in the hemidesmosomes of the epidermis, suggesting its role in epidermal cell-basement membrane adhesion. The clone 450-9D recognizes the extracellular domain of human CD104 and is able to block the binding of clone 439-9B (another CD104 clone) to A431 cells. 450-9D is effective in flow cytometry and immunohistochemistry on frozen sections. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of A431, an epidermal carcinoma cell line, analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD104 - Purified - Clone 450-9D - Isotype Mouse IgG1, λ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 450
- 亚型
- IgG1 lambda
- Top Product
- Discover our top product ITGB4 Primary Antibody
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anti-Integrin beta 4 (ITGB4) (AA 1619-1822) antibody
ITGB4 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 10B10D5 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 29-206) antibodyITGB4 适用: 人 WB, IHC, FACS, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 5G3G5 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 1401-1533) antibodyITGB4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (C-Term) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-310) antibodyITGB4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (Tyr1510) antibodyITGB4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-137) antibodyITGB4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) antibodyITGB4 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal M126 unconjugated
anti-Integrin beta 4 (ITGB4) (pTyr1494) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (pTyr1526) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "A function for the integrin alpha 6 beta 4 in the hemidesmosome." in: Cell regulation, Vol. 2, Issue 6, pp. 427-38, (1991) (PubMed).
: "Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion." in: The Journal of cell biology, Vol. 113, Issue 4, pp. 907-17, (1991) (PubMed).
: "Second generation monoclonal antibodies to the human integrin alpha 6 beta 4." in: Hybridoma, Vol. 9, Issue 3, pp. 243-55, (1990) (PubMed).
: "Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines." in: The Journal of biological chemistry, Vol. 264, Issue 11, pp. 6529-35, (1989) (PubMed).
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: "A function for the integrin alpha 6 beta 4 in the hemidesmosome." in: Cell regulation, Vol. 2, Issue 6, pp. 427-38, (1991) (PubMed).
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- 抗原
- Integrin beta 4 (ITGB4)
- 别名
- CD104 (ITGB4 产品)
- 背景
- Synonyms: Integrin β4 chain
- 途径
- Integrin Complex
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