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- 抗原 See all Cathelicidin (CAMP) 抗体
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
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抗原表位
- AA 115-121
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Cathelicidin antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- H7
- 亚型
- IgG1
- Top Product
- Discover our top product CAMP Primary Antibody
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anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 31-170) antibody
CAMP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal OSX12 unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 31-172) antibodyCAMP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 31-170) antibodyCAMP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (C-Term) antibodyCAMP 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal H7 unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 1-170) antibodyCAMP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- phosphate-buffered solution, pH 7.2, 0.09 % Sodium azide.
- 储存条件
- 4 °C
- 储存方法
- Upon receipt, store undiluted between 2°C and 8°C.
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- 抗原
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
- 别名
- CAP-18 (CAMP 产品)
- 别名
- CAP-18 antibody, CAP18 antibody, CRAMP antibody, FALL-39 antibody, FALL39 antibody, LL37 antibody, CATH-2 antibody, Cnlp antibody, Cramp antibody, MCLP antibody, CATH-B1 antibody, CATHB1 antibody, CATHL2 antibody, CATHL7 antibody, CAP11 antibody, cathelicidin antimicrobial peptide antibody, CAMP antibody, LOC100136187 antibody, LOC100136439 antibody, Camp antibody
- 背景
- Antimicrobial peptides (AMP) are effector molecules of the innate immune system with direct antimicrobioal and immunomodulatory effects. AMP are produced by epithelial and professional host defense cells such as macrophages or neutrophils. AMP directly inactivate microorganisms and, in addition, have diverse activities on various cell types. In mammals, peptides of the defensin and the cathelicidin families are found. hCAP-18 is the only cathelicidin present in humans. hCAP-18 is a 170 amino acid cathelicidin anti-microbial precursor protein that is proteolytically processed to yield the antibacterial peptide LL-37. The precursor hCAP-18 is found in the specific granules of neutrophils and is expressed in many immune and epithelial cells. Cathelicidin has an established role in host defense. In addition to their direct antimicrobial function, cathelicidin peptides are involved in the modulation of repair and tissue homeostasis, epithelial wound healing, chemoattraction of immune cells, and release of inflammatory mediators from epithelial cells. Recent studies also found that LL-37 significantly regulates endocytic capacity, modifies expression of phagocytic receptors, increases secretion of Th1-inducing cytokines of dendritic cells (DC) generated from blood monocytes, and modulates the response of monocytes and DC to toll like receptor (TLR)-ligands. Moreover LL-37 also modulates the response of neutrophils to bacterial activation.
- 途径
- Cellular Response to Molecule of Bacterial Origin
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