IL2 抗体 (Interleukin 2) (Alexa Fluor 700)

Details for Product anti-IL2 Antibody No. ABIN2664046, 供应商: Log in to see
抗原
  • IL2
  • IL-2
  • il2
  • TCGF
  • lymphokine
  • Il-2
  • POIL2
  • interleukin 2
  • IL2
  • il2
  • Il2
适用

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宿主
大鼠
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克隆类型 (克隆位点)
单克隆 ()
标记
This IL2 antibody is conjugated to Alexa Fluor 700
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应用范围
Flow Cytometry (FACS)
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选项
Supplier
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Supplier Product No.
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克隆位点 MQ1-17H12
亚型 IgG2a kappa
交叉反应 Chimpanzee, Baboon, Cynomolgus, 猕猴, Sooty mangabey (Cercocebus atys)
纯化方法 The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 700 under optimal conditions.
别名 IL-2 (IL2 Antibody 摘要)
背景 IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells, promoting proliferation and maturation. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes.
研究领域 Cytokines, Immunology, Virology, Inflammation, Cancer
途径 JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
浓度 0.5 mg/mL
缓冲液 Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Protect from prolonged exposure to light. Do not freeze.
储存条件 4 °C
储存方法 The antibody solution should be stored undiluted between 2°C and 8°C.
厂商提供的图像
Flow Cytometry (FACS) image for anti-Interleukin 2 (IL2) antibody (Alexa Fluor 700) (ABIN2664046) anti-Interleukin 2 (IL2) antibody (Alexa Fluor 700)
背景 Dzhagalov, Chambon, He: "Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 4, pp. 2113-21, 2007 (PubMed).

Raqib, Ekberg, Sharkar, Bardhan, Zychlinsky, Sansonetti, Andersson: "Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2." in: Infection and immunity, Vol. 70, Issue 6, pp. 3199-207, 2002 (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, 1996 (PubMed).

Andersson, Abrams, Björk, Funa, Litton, Agren, Andersson: "Concomitant in vivo production of 19 different cytokines in human tonsils." in: Immunology, Vol. 83, Issue 1, pp. 16-24, 1995 (PubMed).

Fernandez, Andersson, Andersson, Troye-Blomberg: "Cytokine synthesis analyzed at the single-cell level before and after revaccination with tetanus toxoid." in: European journal of immunology, Vol. 24, Issue 8, pp. 1808-15, 1994 (PubMed).

Skansén-Saphir, Andersson, Björk, Andersson: "Lymphokine production induced by streptococcal pyrogenic exotoxin-A is selectively down-regulated by pooled human IgG." in: European journal of immunology, Vol. 24, Issue 4, pp. 916-22, 1994 (PubMed).

Nisticò: "Communications among central nervous system, neuroendocrine and immune systems: interleukin-2." in: Progress in neurobiology, Vol. 40, Issue 4, pp. 463-75, 1993 (PubMed).

Taniguchi, Minami: "The IL-2/IL-2 receptor system: a current overview." in: Cell, Vol. 73, Issue 1, pp. 5-8, 1993 (PubMed).

Waldmann, Goldman, Top, Grant, Burton, Bamford, Roessler, Horak, Zaknoen, Kasten-Sportes: "The interleukin-2 receptor: a target for immunotherapy." in: Annals of the New York Academy of Sciences, Vol. 685, pp. 603-10, 1993 (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).