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HSV ICP27 抗体

HSV ICP27 适用: Herpes Simplex Virus (HSV) WB, IF 宿主: 小鼠 Monoclonal H1113 unconjugated
产品编号 ABIN265583
发货至: 中国
  • 抗原 See all HSV ICP27 products
    HSV ICP27 (Herpes Simplex Virus ICP27 (HSV ICP27))
    适用
    Herpes Simplex Virus (HSV)
    宿主
    • 2
    • 1
    小鼠
    克隆类型
    • 2
    • 1
    单克隆
    标记
    • 3
    This HSV ICP27 antibody is un-conjugated
    应用范围
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Mouse monoclonal antibody to ICP27 of Herpes Simplex Virus. This antibody originates from ascites fluids and is purified by protein G agarose affinity chromatography.
    纯化方法
    Protein G agarose affinity chromatography
    克隆位点
    H1113
    亚型
    IgG1 kappa
  • 应用备注
    Reactive with ICP27 of Herpes Simplex Virus in immunofluorescence (IFA) and western blot at 10 ug/ml.
    限制
    仅限研究用
  • 浓度
    1.0 mg/ml
    缓冲液
    Phosphate Buffered Saline pH 7.4 (no azide)
    储存液
    Azide free
    储存条件
    -20 °C
  • Park, Lengyel, Rice: "The role of immediate-early protein ICP27 in the differential sensitivity of herpes simplex viruses type-1 and type-2 to leptomycin B." in: Journal of virology, (2013) (PubMed).

    Malik, Tabarraei, Kehlenbach, Korfali, Iwasawa, Graham, Schirmer: "Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways." in: The Journal of biological chemistry, Vol. 287, Issue 15, pp. 12277-92, (2012) (PubMed).

    Jurak, Silverstein, Sharma, Coen: "Herpes Simplex Virus Is Equipped with RNA- and Protein-Based Mechanisms To Repress Expression of ATRX, an Effector of Intrinsic Immunity." in: Journal of virology, Vol. 86, Issue 18, pp. 10093-102, (2012) (PubMed).

    Jin, Yan, Ma, Cao, He: "An Herpesvirus Virulence Factor Inhibits Dendritic Cell Maturation Through Protein Phosphatase 1 and I{kappa}B Kinase." in: Journal of virology, (2011) (PubMed).

    Luganini, Nicoletto, Pizzuto, Pirri, Giuliani, Landolfo, Gribaudo: "Inhibition of herpes simplex virus type 1 and type 2 infections by peptide-derivatized dendrimers." in: Antimicrobial agents and chemotherapy, Vol. 55, Issue 7, pp. 3231-9, (2011) (PubMed).

    Salaun, MacDonald, Larralde, Howard, Lochtie, Burgess, Brook, Malik, Gray, Graham: "Poly(A)-binding protein 1 partially relocalizes to the nucleus during herpes simplex virus type 1 infection in an ICP27-independent manner and does not inhibit virus replication." in: Journal of virology, Vol. 84, Issue 17, pp. 8539-48, (2010) (PubMed).

  • 抗原
    HSV ICP27 (Herpes Simplex Virus ICP27 (HSV ICP27))
    Abstract
    HSV ICP27 产品
    物质类
    Viral Protein
    背景
    Herpes simplex virus (HSV) ICP27 (Infected cell polypeptide 27) is an essential and multifunctional regulator of viral gene expression that modulates RNA splicing,polyadenylation, and nuclear export. ICP27 Belongs to the herpes viruses UL69 family. It is involved in the down-regulation of viral immediate-early genes and acts incombination with ICP0 and ICP4 as an activator of late genes. Alternate Names: anti-Herpes simplex virus 1 ICP27 antibody, anti-Herpes simplex virus 1 transcriptional regulator IE63 antibody, anti-Herpes simplex virus 2 ICP27 antibody, anti-Herpessimplex virus 2 transcriptional regulator IE63 antibody
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