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ALOX5AP 抗体

ALOX5AP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4620366
发货至: 中国
  • 抗原 See all ALOX5AP 抗体
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    适用
    • 15
    • 2
    • 1
    宿主
    • 13
    • 3
    克隆类型
    • 15
    • 1
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALOX5AP antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
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    Western Blotting (WB)
    特异性
    This antibody detects FLAP.
    Cellular Localization: Nucleus membrane. Endoplasmic reticulum membrane.
    纯化方法
    Antigen Immunoaffiinity Chromatography
    免疫原
    Synthetic peptide derived from Human FLAP protein
    Top Product
    Discover our top product ALOX5AP Primary Antibody
  • 应用备注
    Western blot (1: 400 starting dilution).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.08 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Can be shipped at 2-8 °C.
  • 抗原
    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
    别名
    ALOX5AP / FLAP (ALOX5AP 产品)
    别名
    fj65d02 antibody, zgc:63982 antibody, wu:fj65d02 antibody, flap antibody, al5ap antibody, Alox5ap antibody, ALOX5AP antibody, Flap antibody, FLAP antibody, arachidonate 5-lipoxygenase-activating protein antibody, arachidonate 5-lipoxygenase activating protein antibody, alox5ap antibody, ALOX5AP antibody, Alox5ap antibody
    背景
    Genetic variations in ALOX5AP may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Note=Genetic variations in ALOX5AP may be associated with susceptibility to myocardial infarction. Involvement in myocardial infarction is however unclear: according to some authors (PubMed:14770184), a 4-SNP haplotype in ALOX5AP confers risk of myocardial infarction, while according to other (PubMed:17304054) ALOX5AP is not implicated in this condition. Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.Synonyms: Arachidonate 5-lipoxygenase-activating protein, MK-886-binding protein
    基因ID
    241
    NCBI登录号
    NP_001191335
    UniProt
    P20292
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