(1 reference)-
- 抗原 See all SET/TAF-I (SET) 抗体
- SET/TAF-I (SET) (SET Nuclear Oncogene (SET))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SET/TAF-I antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects I2PP2A / SET, widely expressed. Low levels in quiescent cells during serum starvation, contact inhibition or differentiation. Highly expressed in Wilms' tumor.
- 纯化方法
- Affinity chromatography
- 免疫原
- Synthetic peptide derived from the human SET protein
- 亚型
- IgG
- Top Product
- Discover our top product SET Primary Antibody
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anti-SET Nuclear Oncogene (SET) (N-Term) antibody
Verified SET 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) (AA 1-277) antibodySET 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) antibodySET 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) (AA 146-277) antibodySET 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) antibodySET 适用: 人, 小鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) (AA 1-277) antibodySET 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal M1-F5 unconjugated
anti-SET Nuclear Oncogene (SET) (N-Term) antibodySET 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) antibodySET 适用: 人, 小鼠, 大鼠 WB, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) (AA 147-235) antibodySET 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SET Nuclear Oncogene (SET) (AA 35-84) antibodySET 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 非洲爪蟾, 斑马鱼, 马, 兔, 豚鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot (1: 400 dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the product (in aliquots) at -20 °C to -70 °C. Can be shipped at 2 - 8 °C.
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: "Particle size distributions and health-related exposures of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) of sinter plant workers." in: Chemosphere, (2009) (PubMed).
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: "Particle size distributions and health-related exposures of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) of sinter plant workers." in: Chemosphere, (2009) (PubMed).
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- 抗原
- SET/TAF-I (SET) (SET Nuclear Oncogene (SET))
- 别名
- SET / I2PP2A (SET 产品)
- 别名
- 2PP2A antibody, I2PP2A antibody, IGAAD antibody, IPP2A2 antibody, PHAPII antibody, TAF-I antibody, TAF-IBETA antibody, 2610030F17Rik antibody, 5730420M11Rik antibody, AA407739 antibody, I-2PP2A antibody, StF-IT-1 antibody, 2pp2a antibody, i2pp2a antibody, igaad antibody, ipp2a2 antibody, phapii antibody, set antibody, set-a antibody, set-b antibody, taf-ibeta antibody, wu:fb30g11 antibody, wu:fd16c08 antibody, SET nuclear proto-oncogene antibody, SET nuclear oncogene antibody, SET translocation antibody, SET nuclear proto-oncogene L homeolog antibody, SET nuclear proto-oncogene b antibody, SET antibody, Set antibody, LOC403555 antibody, set.L antibody, setb antibody
- 背景
- Human SET was originally identified as part of the SET-CAN fusion gene produced by a somatic translocation event in a patient with acute undifferentiated leukemia. In developing kidney, SET is highly expressed in the zone of nephron morphogenesis. SET has been shown to be a potent and specific inhibitor of protein phosphatase 2A, a family of major serine/threonine phosphatases involved in regulating cell proliferation and differentiation. SET is also involved in the regulation of renal cell proliferation and tumorigenesis. SET mRNA expression is markedly reduced in cells rendered quiescent by serum starvation, contact inhibition, or differentiation. SET protein expression is also much greater in developing rat and human kidney than in fully differentiated, mature kidney. High levels of SET mRNA and SET protein expression arefound in Wilms' tumor, but not in renal cell carcinoma, adult polycystic kidney disease or in transitional cell carcinoma.Synonyms: I-2PP2A, IGAAD, Inhibitor of granzyme A-activated DNase, PHAPII, Phosphatase 2A inhibitor I2PP2A, TAF-I, Template-activating factor I
- 基因ID
- 6418
- NCBI登录号
- NP_001116293
- UniProt
- H0UI37
- 途径
- Apoptosis
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