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TLR3 抗体 (N-Term)

TLR3 适用: 人, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265140
发货至: 中国
  • 抗原 See all TLR3 抗体
    TLR3 (Toll-Like Receptor 3 (TLR3))
    抗原表位
    • 16
    • 10
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    • 5
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    N-Term
    适用
    • 99
    • 66
    • 31
    • 6
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 86
    • 31
    • 3
    • 2
    克隆类型
    • 89
    • 33
    多克隆
    标记
    • 54
    • 18
    • 15
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR3 antibody is un-conjugated
    应用范围
    • 85
    • 43
    • 38
    • 35
    • 24
    • 18
    • 15
    • 15
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
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    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Purified
    免疫原
    Peptide corresponding to 15 amino acids near the amino terminus of human TLR3
    亚型
    IgG
    Top Product
    Discover our top product TLR3 Primary Antibody
  • 应用备注
    Western Blot: 1 to 2 μg/mL: K562 cell lysate can be used as a positive control. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原
    TLR3 (Toll-Like Receptor 3 (TLR3))
    别名
    CD283 / TLR3 (TLR3 产品)
    别名
    CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
    背景
    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (3) so the organism can respond to potential infection. TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection (4). Recently it has been shown to recognize viruses such as Influenza A (5) and West Nile Virus and can mediate entry of at least West Nile Virus (6). TLR3 is ocated in the membrane and expressed at high level in placenta and pancreas. Also detected in CD11c+ immature dendritic cells. Only expressed in dendritic cells and not in other leukocytes, including monocyte precursors.(7)Synonyms: Toll-like receptor 3
    基因ID
    9606
    UniProt
    O15455
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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