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LY96 抗体 (Middle Region)

LY96 适用: 人, 小鼠, 大鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265133
发货至: 中国
  • 抗原 See all LY96 抗体
    LY96 (Lymphocyte Antigen 96 (LY96))
    抗原表位
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 56
    • 12
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 41
    • 19
    克隆类型
    • 44
    • 16
    多克隆
    标记
    • 29
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LY96 antibody is un-conjugated
    应用范围
    • 42
    • 22
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Purified
    免疫原
    Rabbit polyclonal MD-2 antibody was raised against a peptide corresponding to amino acids near the middle region of human MD-2.
    亚型
    IgG
    Top Product
    Discover our top product LY96 Primary Antibody
  • 应用备注
    Western Blot: 0,5 - 1 μg/mL. Immunohistochemistry. Found in the liver and spleen, the secreted protein Lymphocyte antigen 96/MD-2ooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS),and with TLR2 in the response to cell wall components from Gram-positive andGram-negative bacteria.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    LY96 (Lymphocyte Antigen 96 (LY96))
    别名
    MD-2 (LY96 产品)
    别名
    MD2 antibody, ESOP-1 antibody, MD-2 antibody, ly-96 antibody, Ly-96 antibody, Md2 antibody, lymphocyte antigen 96 antibody, LY96 antibody, Ly96 antibody
    背景
    MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1 - 3). TLRs are signaling molecules that recognize different pathogenassociated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS (5,6). The specificity of this response is determined by the species of MD-2, e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4 (7).Synonyms: ESOP-1, ESOP1, LY96, Lymphocyte antigen 96, MD2
    基因ID
    9606
    UniProt
    Q9Y6Y9
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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