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MAPKBP1 抗体

MAPKBP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2650930
发货至: 中国
  • 抗原 See all MAPKBP1 抗体
    MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
    适用
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 7
    • 1
    克隆类型
    • 8
    多克隆
    标记
    • 8
    This MAPKBP1 antibody is un-conjugated
    应用范围
    • 7
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human MAPKBP1
    亚型
    IgG
    Top Product
    Discover our top product MAPKBP1 Primary Antibody
  • 应用备注
    WB 1:200 - 1:500
    IHC 1:50 - 1:100
    说明

    Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20C. Avoid freeze / thaw cycles.
  • 抗原
    MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
    别名
    MAPKBP1 (MAPKBP1 产品)
    别名
    MGC83682 antibody, JNKBP-1 antibody, 2810483F24Rik antibody, AW123212 antibody, Jnkbp1 antibody, mKIAA0596 antibody, mitogen-activated protein kinase binding protein 1 L homeolog antibody, mitogen-activated protein kinase binding protein 1 antibody, mitogen activated protein kinase binding protein 1 antibody, mapkbp1.L antibody, MAPKBP1 antibody, Mapkbp1 antibody
    背景
    This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
    分子量
    163.818 kDa
    基因ID
    23005
    UniProt
    O60336
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