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VSX2 抗体 (N-Term)

VSX2 适用: 小鼠, 大鼠 WB, IHC (fro) 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN265011
发货至: 中国
  • 抗原 See all VSX2 抗体
    VSX2 (Visual System Homeobox 2 (VSX2))
    抗原表位
    • 11
    • 9
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-131, N-Term
    适用
    • 38
    • 16
    • 6
    • 1
    小鼠, 大鼠
    宿主
    • 39
    • 6
    • 1
    绵羊
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 23
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VSX2 antibody is un-conjugated
    应用范围
    • 39
    • 16
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognizes chx 10 (N-Term).
    纯化方法
    Purified
    免疫原
    Antibody raised against a recombinant protein corresponding to amino acids 1 to 131 derived from the N terminal of the human Chx10 protein conjugated to GST.
    亚型
    IgG
    Top Product
    Discover our top product VSX2 Primary Antibody
  • 应用备注
    Western Blot: 0.5-1.0 mg/mL. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.08 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Can be shipped at ambient temperature.
  • Bai, Kiyama, Li, Wang: "Birth of cone bipolar cells, but not rod bipolar cells, is associated with existing RGCs." in: PLoS ONE, Vol. 9, Issue 1, pp. e83686, (2014) (PubMed).

    Haynes, Luz-Madrigal, Reis, Echeverri Ruiz, Grajales-Esquivel, Tzekou, Tsonis, Lambris, Del Rio-Tsonis: "Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration." in: Nature communications, Vol. 4, pp. 2312, (2013) (PubMed).

    Tiwari, Hudson, Gattone, Miller, Chernoff, Belecky-Adams: "Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome." in: PLoS ONE, Vol. 8, Issue 3, pp. e59306, (2013) (PubMed).

    Luo, Jin, Xie, Qiu, Li, Zou, Cai, Hozumi, Shima, Xiang: "Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 9, pp. E553-62, (2012) (PubMed).

    Sherry, Kanan, Hamilton, Hoffhines, Arbogast, Fliesler, Naash, Moore, Al-Ubaidi: "Differential developmental deficits in retinal function in the absence of either protein tyrosine sulfotransferase-1 or -2." in: PLoS ONE, Vol. 7, Issue 6, pp. e39702, (2012) (PubMed).

    Wakabayashi, Kosaka, Mori, Yamada: "Prolonged expression of Puma in cholinergic amacrine cells during the development of rat retina." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 60, Issue 10, pp. 777-88, (2012) (PubMed).

    Nittner, Lambertz, Clermont, Mestdagh, Köhler, Nielsen, Jochemsen, Speleman, Vandesompele, Dyer, Schramm, Schulte, Marine: "Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation." in: Nature cell biology, Vol. 14, Issue 9, pp. 958-65, (2012) (PubMed).

    Elshatory, Everhart, Deng, Xie, Barlow, Gan: "Islet-1 controls the differentiation of retinal bipolar and cholinergic amacrine cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 46, pp. 12707-20, (2007) (PubMed).

    Osakada, Ooto, Akagi, Mandai, Akaike, Takahashi: "Wnt signaling promotes regeneration in the retina of adult mammals." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 15, pp. 4210-9, (2007) (PubMed).

    Yun, Sun, Wang, Rusovici, Castleberry, Hall, Shim: "LPA2 receptor mediates mitogenic signals in human colon cancer cells." in: American journal of physiology. Cell physiology, Vol. 289, Issue 1, pp. C2-11, (2005) (PubMed).

    Dorsam, Graeler, Seroogy, Kong, Voice, Goetzl: "Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 7, pp. 3500-7, (2003) (PubMed).

  • 抗原
    VSX2 (Visual System Homeobox 2 (VSX2))
    别名
    VSX2 / CHX10 (VSX2 产品)
    别名
    CHX10 antibody, HOX10 antibody, MCOP2 antibody, MCOPCB3 antibody, RET1 antibody, Chx10 antibody, Hox-10 antibody, Hox10 antibody, or antibody, VSX2 antibody, Vsx-2 antibody, alx antibody, chx10 antibody, c-ret antibody, cret antibody, etID315074.13 antibody, ret1 antibody, wu:fd13h01 antibody, visual system homeobox 2 antibody, ret proto-oncogene receptor tyrosine kinase antibody, Vsx2 transcription factor antibody, VSX2 antibody, Vsx2 antibody, vsx2 antibody, ret antibody
    背景
    Chx10 is a 46 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.Synonyms: Ceh-10 homeodomain-containing homolog, HOX10, Homeobox protein CHX10, Visual system homeobox 2
    分子量
    46 kDa
    基因ID
    12677
    NCBI登录号
    NP_031727
    UniProt
    Q61412
    途径
    Dopaminergic Neurogenesis
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