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CCR5 抗体 (AA 6-20)

CCR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265000
发货至: 中国
  • 抗原 See all CCR5 抗体
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    抗原表位
    • 16
    • 13
    • 12
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-20
    适用
    • 139
    • 40
    • 39
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 104
    • 30
    • 13
    • 4
    克隆类型
    • 107
    • 38
    • 3
    多克隆
    标记
    • 83
    • 15
    • 10
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR5 antibody is un-conjugated
    应用范围
    • 95
    • 66
    • 55
    • 20
    • 19
    • 17
    • 16
    • 14
    • 14
    • 13
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to CCR5 (6-20) (CD195).
    纯化方法
    Antigen Immunoaffiinity Chromatography
    免疫原
    Synthetic peptide corresponding to amino acids 6 to 20 of Human CCR5.
    亚型
    IgG
    Top Product
    Discover our top product CCR5 Primary Antibody
  • 应用备注
    Western Blot: 0.25 to 0.5 μg/mL. Detects an approximately 40 kDa band in THP-1 whole celllysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline solution containing 0.02 % Sodium Azide as a preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
  • 抗原
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    别名
    CD195 / CCR5 (CCR5 产品)
    别名
    CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
    背景
    Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors1,2. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells3,4. CCR5 is required for the infection by HIV-1, HIV-2, and SIV1,2. The b-chemokines RANTES, MIP-1a and MIP-1b are the ligands for CCR5 and prevent infection by M-tropic HIV-13-5. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells6,7. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites8. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor
    基因ID
    1234
    NCBI登录号
    NP_000570
    UniProt
    P51681
    途径
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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