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Acetylated Lysine 抗体 (acetylated) (HRP)

WB, IP, IF, EIA 宿主: 兔 Polyclonal HRP
产品编号 ABIN264879
发货至: 中国
  • 抗原 See all Acetylated Lysine products
    Acetylated Lysine
    抗原表位
    • 9
    • 1
    • 1
    acetylated
    适用
    请咨询
    宿主
    • 28
    • 22
    克隆类型
    • 26
    • 23
    多克隆
    标记
    • 22
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Acetylated Lysine antibody is conjugated to HRP
    应用范围
    • 49
    • 39
    • 34
    • 22
    • 12
    • 12
    • 11
    • 11
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity Chromatography
    免疫原
    Acetylated KLH
    亚型
    IgG
  • 应用备注
    Western blot (6). Immunoprecipitation (7). ELISA. Immonoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide, 50 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Acetylated Lysine
    Abstract
    Acetylated Lysine 产品
    别名
    C-K-RAS antibody, CFC2 antibody, K-RAS2A antibody, K-RAS2B antibody, K-RAS4A antibody, K-RAS4B antibody, KI-RAS antibody, KRAS1 antibody, KRAS2 antibody, NS antibody, NS3 antibody, RASK2 antibody, KRAS proto-oncogene, GTPase antibody, KRAS antibody
    物质类
    Chemical
    背景
    Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine N?-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that plays critical roles in regulating gene transcription, cell-cycle progression, apoptosis, DNA repair, and cytoskeletal organization (3). The regulation of protein acetylation status is impaired in the pathologies of cancer and polyglutamine diseases (4), and HDACs have become promising targets for anticancer drugs currently in development (5).Synonyms: AcK, acetyl Lysine, acetyl-Lysine
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