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Caspase 7 抗体

CASP7 适用: 人 WB 宿主: 小鼠 Monoclonal MCH3 14 1-11 unconjugated
产品编号 ABIN264406
发货至: 中国
  • 抗原 See all Caspase 7 (CASP7) 抗体
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    适用
    • 79
    • 53
    • 28
    • 6
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    • 4
    • 3
    • 3
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    • 2
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    • 2
    • 1
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    宿主
    • 76
    • 13
    • 1
    小鼠
    克隆类型
    • 74
    • 16
    单克隆
    标记
    • 62
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
    This Caspase 7 antibody is un-conjugated
    应用范围
    • 86
    • 31
    • 26
    • 21
    • 14
    • 13
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
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    Western Blotting (WB)
    特异性
    Detects human Caspase-7 by Western blot.
    产品特性
    Synonyms: CASP-7, CASP7, MCH3, CMH-1, ICE-like apoptotic protease 3, Apoptotic protease Mch-3
    纯化方法
    Purified
    免疫原
    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinanthuman capase-7 protein and mouse myeloma cells. Genename: CASP7
    克隆位点
    MCH3 14 1-11
    亚型
    IgG1
    Top Product
    Discover our top product CASP7 Primary Antibody
  • 应用备注
    Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.08 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    别名
    Caspase-7 (CASP7 产品)
    别名
    xCaspase-7 antibody, caspase-7 antibody, caspase7 antibody, cmh-1 antibody, ice-lap3 antibody, mch3 antibody, CASP7 antibody, AI314680 antibody, CMH-1 antibody, ICE-IAP3 antibody, Mch3 antibody, mCASP-7 antibody, CASP-7 antibody, ICE-LAP3 antibody, LICE2 antibody, MCH3 antibody, Caspase-7 antibody, MCH3/SCA-2 antibody, SCA-2 antibody, caspase 7 antibody, caspase-7 antibody, caspase 7 S homeolog antibody, CASP7 antibody, xcaspase-7 antibody, casp7 antibody, casp7.S antibody, Casp7 antibody
    背景
    Caspases are key effectors of programmed cell death. Caspase-7 along with caspase 3 and 6 form the group of effector caspases that are responsible for the cleavage of multiple substrates including the cytokeratins, PARP, alpha fodrin, NuMA and others. Caspase-7 is a 303 amino acid protein with high similarity to caspase-3. Caspase-7 occurs in three varient forms. Granzyme B activates pro-caspase-7 to a form which can cleave poly(ADP-ribose) polymerase (PARP) to its signature fragment of ~85 kDa. Also, in vivo caspase-7 appears to be a better substrate for granzyme B than caspase-3. Pro-caspase-7 has been shown to exist as dimers or high order oligomers. Caspase-7 may be an important intracellular effector of granzyme B-mediated apoptosis and cytotoxic T-lymophocyte-induced cell killing in vivo.Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
    基因ID
    840
    UniProt
    P55210
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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