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PTGES3 抗体

PTGES3 适用: 人, 小鼠, 豚鼠, 兔, 小鸡, Saccharomyces cerevisiae WB, IHC (p), IP, EIA 宿主: 小鼠 Monoclonal JJ6 unconjugated
产品编号 ABIN263974
发货至: 中国
  • 抗原 See all PTGES3 抗体
    PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))
    适用
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    人, 小鼠, 豚鼠, 兔, 小鸡, Saccharomyces cerevisiae
    宿主
    • 58
    • 6
    小鼠
    克隆类型
    • 57
    • 7
    单克隆
    标记
    • 33
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    This PTGES3 antibody is un-conjugated
    应用范围
    • 55
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ~23 kDa p23.
    产品特性
    Synonyms: Prostaglandin E synthase 3, cPGES, P23, Cytosolic prostaglandin E2 synthase,Telomerase-binding protein p23, Hsp90 co-chaperone, Progesterone receptor complex p23
    纯化方法
    Protein G Affinity Chromatography
    免疫原
    Recombinant Human full length p23 protein
    克隆位点
    JJ6
    亚型
    IgG1
    Top Product
    Discover our top product PTGES3 Primary Antibody
  • 应用备注
    Western blot (1: 2000). Immunprecipitation. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS in 50 % Glycerol, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))
    别名
    PTGES3 / TEBP (PTGES3 产品)
    别名
    P23 antibody, TEBP antibody, cPGES antibody, PTGES3 antibody, 5730442A20Rik antibody, Ptges antibody, Tebp antibody, p23 antibody, sid3177 antibody, RGD1561913 antibody, CPGES antibody, cPGES-1 antibody, ptges3 antibody, wu:fb98d06 antibody, zgc:65804 antibody, zgc:77131 antibody, tebp antibody, wu:fb50a04 antibody, zgc:86751 antibody, prostaglandin E synthase 3 antibody, prostaglandin E synthase 3 (cytosolic) pseudogene antibody, prostaglandin E synthase 3a (cytosolic) antibody, prostaglandin E synthase 3 L homeolog antibody, prostaglandin E synthase 3b (cytosolic) antibody, PTGES3 antibody, LOC743066 antibody, Ptges3 antibody, ptges3a antibody, ptges3.L antibody, ptges3b antibody
    背景
    P23 is a highly conserved ubiquitous protein, known to have an important function as a cochaperone for the hsp90 chaperoning system (1). Studies have revealed that p23 is a small protein (18 to 25 kDa) with a simple structure (2, 3). p23 does not have any structural homology with any other known proteins (1). p23 was first discovered as a part of the Hsp90-progesterone receptor complex along with hsp70, p54 and p50 (1). p23 is a phosphor-protein, which is highly acidic and has an aspartic acid-rich c-terminal domain (1). Numerous studies have found p23 to be associated with other client proteins like Fes tyrosine kinase (4), the heme regulated kinase HRI (5), hsf1 transcription factor (4), aryl hydrocarbon receptor (4), telomerase (6), and Hepadnavirus reverse transcriptase (7). In spite of several years of study, the exact functional significance of p23 is still not clear (8). p23 is thought to be involved in the adenosine triphosphate-mediated hsp90 binding of client proteins (8). Since many hsp90 client proteins are involved in oncogenic survival signaling, a recent study has concluded p23 to be a promising target in leukemic apoptosis (9). Hsp90 and its co-chaperone p23 are certainly among the emerging anti-tumor targets in oncology.Synonyms: Cytosolic prostaglandin E2 synthase, Hsp90 co-chaperone, P23, Progesterone receptor complex p23, Prostaglandin E synthase 3, Telomerase-binding protein p23, cPGES
    基因ID
    10728
    UniProt
    Q15185
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Cellular Glucan Metabolic Process
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