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Piccolo 抗体 (HRP)

PIC 适用: 人 WB, IHC 宿主: 兔 Polyclonal HRP
产品编号 ABIN2482400
发货至: 中国
  • 抗原 See all Piccolo (PIC) products
    Piccolo (PIC)
    适用
    • 22
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    • 1
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    • 1
    宿主
    • 18
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    • 1
    • 1
    克隆类型
    • 20
    • 15
    多克隆
    标记
    • 15
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    • 2
    • 2
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    This Piccolo antibody is conjugated to HRP
    应用范围
    • 33
    • 16
    • 15
    • 13
    • 11
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Detects ~550 kDa. No cross-reactivity to Bassoon.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein A Purified
    免疫原
    Recombinant Full length Protein, BC001304.1
  • 应用备注
    • WB (1:1000)
    • IHC (1:400)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2482400 was sufficient for detection of Piccolo in 10 μg of rat brain tissue lysate by colorimetric immunoblot analysis using goat ant rabbit IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    Piccolo (PIC)
    别名
    Piccolo (PIC 产品)
    背景
    Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains (1, 2). In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) (3). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 (2).
    基因ID
    27445
    NCBI登录号
    NP_055325
    UniProt
    Q9Y6V0
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