TRAP1 抗体 (AA 1-59) (HRP)
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- 抗原 See all TRAP1 抗体
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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抗原表位
- AA 1-59
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRAP1 antibody is conjugated to HRP
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~75 kDa, multiple isoforms.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein A Purified
- 免疫原
- Human recombinant TRAP1 (amino acids 1-59 removed - transit peptide)
- Top Product
- Discover our top product TRAP1 Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:120)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2482022 was sufficient for detection of Trap-1 in 20 μg of Hela Cell lysate by ECL immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- 别名
- TRAP1 (TRAP1 产品)
- 别名
- HSP 75 antibody, HSP75 antibody, HSP90L antibody, TRAP-1 antibody, 2410002K23Rik antibody, fc85a11 antibody, wu:fc85a11 antibody, TNF receptor associated protein 1 antibody, TNF receptor-associated protein 1 antibody, TRAP1 antibody, Trap1 antibody, trap1 antibody
- 背景
- The 90 kDa heat shock protein (HSP90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role. HSP90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of HSP90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like HSP90, TRAP1 is found to beassociated with numerous proteins involved in diverse actions (1, 2). Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein (3).
- 基因ID
- 10131
- NCBI登录号
- NP_057376
- UniProt
- Q12931
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