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MNDA 抗体

MNDA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458298
发货至: 中国
  • 抗原 See all MNDA 抗体
    MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
    适用
    • 38
    • 3
    • 1
    宿主
    • 35
    • 4
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This MNDA antibody is un-conjugated
    应用范围
    • 27
    • 23
    • 22
    • 14
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MNDA.
    Top Product
    Discover our top product MNDA Primary Antibody
  • 应用备注
    MNDA antibody can be used for detection of MNDA by ELISA at 1:1562500. MNDA antibody can be used for detection of MNDA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MNDA antibody at -20 °C.
  • 抗原
    MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
    别名
    MNDA (MNDA 产品)
    别名
    PYHIN3 antibody, A730048F03 antibody, Ifi205b antibody, myeloid cell nuclear differentiation antigen antibody, interferon activated gene 211 antibody, MNDA antibody, Ifi211 antibody
    背景
    The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage.MNDA may act as a transcriptional activator/repressor in the myeloid lineage. It plays a role in the granulocyte/monocyte cell-specific response to interferon. MNDA stimulates the DNA binding of the transcriptional repressor protein YY1.The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    分子量
    46 kDa
    基因ID
    4332
    NCBI登录号
    NP_002423
    UniProt
    P41218
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