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SUMO1 抗体 (full length) (FITC)

SUMO1 适用: 人 WB, IF, IHC (p) 宿主: 大鼠 Monoclonal 4D12 FITC
产品编号 ABIN2452136
发货至: 中国
  • 抗原 See all SUMO1 抗体
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    抗原表位
    • 15
    • 15
    • 15
    • 15
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length
    适用
    • 117
    • 89
    • 67
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 120
    • 31
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠
    克隆类型
    • 115
    • 43
    单克隆
    标记
    • 72
    • 13
    • 10
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SUMO1 antibody is conjugated to FITC
    应用范围
    • 124
    • 65
    • 45
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    • 40
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    • 32
    • 26
    • 16
    • 12
    • 9
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Specific to human, simian, mouse and rat SUMO1.
    交叉反应 (详细)
    Not tested for other species
    纯化方法
    The antibody was produced in serum-free medium and purified by proprietary chromatography procedures under mild conditions and conjugated with FITC.
    过滤
    Sterile filtered
    免疫原
    Recombinant GST-fused human SUMO-1 (full length)
    克隆位点
    4D12
    亚型
    IgG2a kappa
    Top Product
    Discover our top product SUMO1 Primary Antibody
  • 应用备注
    1. Immunofluorescence staining: 1/100 dilution
    2. Immunohistochemistry,frozen section: 1/100 dilution
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (x1), 50 % glycerol. Azide and carrier free.
    储存液
    Azide free
    储存条件
    -20 °C
  • Ulrich: "The fast-growing business of SUMO chains." in: Molecular cell, Vol. 32, Issue 3, pp. 301-5, (2008) (PubMed).

    Saitoh, Uchimura, Tachibana, Sugahara, Saitoh, Nakao: "In situ SUMOylation analysis reveals a modulatory role of RanBP2 in the nuclear rim and PML bodies." in: Experimental cell research, Vol. 312, Issue 8, pp. 1418-30, (2006) (PubMed).

    Cheng, Bawa, Lee, Gong, Yeh: "Role of desumoylation in the development of prostate cancer." in: Neoplasia (New York, N.Y.), Vol. 8, Issue 8, pp. 667-76, (2006) (PubMed).

    Uchimura, Ichimura, Uwada, Tachibana, Sugahara, Nakao, Saitoh: "Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation." in: The Journal of biological chemistry, Vol. 281, Issue 32, pp. 23180-90, (2006) (PubMed).

  • 抗原
    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
    别名
    SUMO1 (SUMO1 产品)
    别名
    DAP1 antibody, GMP1 antibody, OFC10 antibody, PIC1 antibody, SENP2 antibody, SMT3 antibody, SMT3C antibody, SMT3H3 antibody, UBL1 antibody, hm:zeh0670 antibody, wu:fb74c02 antibody, wu:fd12c02 antibody, zgc:65934 antibody, zgc:85634 antibody, SUMO1 antibody, dap1 antibody, gmp1 antibody, ofc10 antibody, pic1 antibody, senp2 antibody, smt3 antibody, smt3c antibody, sumo-1 antibody, sumo1 antibody, ubl1 antibody, xsumo-1 antibody, xsumo1 antibody, ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, ATSUMO1 antibody, F10M23.180 antibody, F10M23_180 antibody, SMALL UBIQUITIN-LIKE MODIFIER 1 antibody, SUM1 antibody, SUMO 1 antibody, small ubiquitin-like modifier 1 antibody, pigSUMO1 antibody, SENTRIN antibody, SMTP3 antibody, SUMO-1 antibody, Smt3C antibody, Ubl1 antibody, small ubiquitin-like modifier 1 antibody, small ubiquitin-like modifier 1 S homeolog antibody, small ubiquitin-related protein 1 antibody, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) antibody, SMT3 suppressor of mif two 3 homolog 1 (yeast) antibody, small ubiquitin-like modifier 1 L homeolog antibody, Sumo1 antibody, SUMO1 antibody, sumo1 antibody, sumo1.S antibody, sumo-1 antibody, sumo1.L antibody
    背景
    SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. Unlike ubiquitination, which targets proteins for degradation, SUMO modification plays a critical role in a number of cellular functions including nucleocytoplasmic transport, gene expression, cell cycle and formation of subnuclear structures such as promyelocytic leukemia (PML) bodies. There are three confirmed SUMO isoforms in human, SUMO1, SUMO2 and SUMO3. SUMO2 /3 show a high degree of similarity to each other and are distinct from SUMO-1. Individual SUMO family members are all targeted to different proteins with diverse biological functions. SUMO-1 is conjugated to RanGAP, PML, p53 and IkappaB-alpha to regulate nuclear trafficking, formation of subnuclear structures, regulation of transcriptional activity and protein stability. SUMO1 is encoded as a 101 aa protein and first Met and C-terminal 4 aa are removed from the preprotein.
    UniProt
    P63165
    途径
    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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