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CRHR1 抗体 (AA 107-117)

Verified CRHR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN238557
发货至: 中国
  • 抗原 See all CRHR1 抗体
    CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
    抗原表位
    • 15
    • 15
    • 9
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-117
    适用
    • 63
    • 63
    • 61
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 87
    • 5
    • 1
    山羊
    克隆类型
    • 88
    • 5
    多克隆
    标记
    • 36
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This CRHR1 antibody is un-conjugated
    应用范围
    • 75
    • 37
    • 29
    • 26
    • 20
    • 16
    • 11
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    原理
    CRHR1 / CRF-R (aa 107 - 117)
    序列
    NEEKKSKVHY H
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    质量等级
    Verified
    免疫原
    Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.
    亚型
    IgG
  • 应用备注

    Western Blot: Approx 60 kDa band observed in Human Brain (Cerebellum), Colon, Rat Brain and Mouse spinal cord lysates (calculated MW of 47.7 kDa according to NP_004373.2). The observed molecular weight corresponds to earlier findings in literature with di

    Peptide ELISA: antibody detection limit dilution 1:128000.

    说明

    Immunofluorescence: Expression of the protein seen in the membranes, vesicles and cytoplasm of MCF7 and Neuro2a cells. Recommended concentration: 10μg/ml.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Xie, Penzes, Srivastava: "Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss." in: The European journal of neuroscience, Vol. 50, Issue 7, pp. 3108-3114, (2020) (PubMed).

    Jüngling, Liu, Lesting, Coulon, Sosulina, Reinscheid, Pape: "Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor." in: The Journal of physiology, Vol. 590, Issue Pt 16, pp. 3701-17, (2012) (PubMed).

    Weerachayaphorn, Mennone, Soroka, Harry, Hagey, Kensler, Boyer: "Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 9, pp. G925-36, (2012) (PubMed).

  • 抗原
    CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
    别名
    CRHR1 (CRHR1 产品)
    别名
    CRF-R antibody, CRF-R-1 antibody, CRF-R1 antibody, CRF1 antibody, CRFR-1 antibody, CRFR1 antibody, CRH-R-1 antibody, CRH-R1 antibody, CRH-R1h antibody, CRHR antibody, CRHR1L antibody, CRHR1f antibody, Crhr antibody, crhr1 antibody, crhr1-A antibody, CRHR1 antibody, CRHR1-IT1-CRHR1 antibody, MGC57346-CRHR1 antibody, corticotropin releasing hormone receptor 1 antibody, corticotropin releasing hormone receptor 1, gene 2 S homeolog antibody, corticotropin-releasing factor receptor 1 antibody, LINC02210-CRHR1 readthrough antibody, CRHR1 antibody, Crhr1 antibody, crhr1.2.S antibody, LOC610380 antibody, LOC100065598 antibody, LINC02210-CRHR1 antibody, crhr1 antibody
    背景
    CRHR1, CRF-R, corticotropin releasing hormone receptor 1, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f, corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor
    基因ID
    1394, 12921, 58959
    NCBI登录号
    NP_004373
    途径
    Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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