CRHR1 抗体 (AA 107-117)
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- 抗原 See all CRHR1 抗体
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
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抗原表位
- AA 107-117
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适用
- 人, 小鼠, 大鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This CRHR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 原理
- CRHR1 / CRF-R (aa 107 - 117)
- 序列
- NEEKKSKVHY H
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- 质量等级
- Verified
- 免疫原
- Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.
- 亚型
- IgG
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- 应用备注
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Western Blot: Approx 60 kDa band observed in Human Brain (Cerebellum), Colon, Rat Brain and Mouse spinal cord lysates (calculated MW of 47.7 kDa according to NP_004373.2). The observed molecular weight corresponds to earlier findings in literature with di
Peptide ELISA: antibody detection limit dilution 1:128000.
- 说明
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Immunofluorescence: Expression of the protein seen in the membranes, vesicles and cytoplasm of MCF7 and Neuro2a cells. Recommended concentration: 10μg/ml.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Minimize freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss." in: The European journal of neuroscience, Vol. 50, Issue 7, pp. 3108-3114, (2020) (PubMed).
: "Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor." in: The Journal of physiology, Vol. 590, Issue Pt 16, pp. 3701-17, (2012) (PubMed).
: "Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 9, pp. G925-36, (2012) (PubMed).
: "
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Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss." in: The European journal of neuroscience, Vol. 50, Issue 7, pp. 3108-3114, (2020) (PubMed).
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- 抗原
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- 别名
- CRHR1 (CRHR1 产品)
- 别名
- CRF-R antibody, CRF-R-1 antibody, CRF-R1 antibody, CRF1 antibody, CRFR-1 antibody, CRFR1 antibody, CRH-R-1 antibody, CRH-R1 antibody, CRH-R1h antibody, CRHR antibody, CRHR1L antibody, CRHR1f antibody, Crhr antibody, crhr1 antibody, crhr1-A antibody, CRHR1 antibody, CRHR1-IT1-CRHR1 antibody, MGC57346-CRHR1 antibody, corticotropin releasing hormone receptor 1 antibody, corticotropin releasing hormone receptor 1, gene 2 S homeolog antibody, corticotropin-releasing factor receptor 1 antibody, LINC02210-CRHR1 readthrough antibody, CRHR1 antibody, Crhr1 antibody, crhr1.2.S antibody, LOC610380 antibody, LOC100065598 antibody, LINC02210-CRHR1 antibody, crhr1 antibody
- 背景
- CRHR1, CRF-R, corticotropin releasing hormone receptor 1, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f, corticotropin releasing hormone receptor variant 1h, seven transmembrane helix receptor
- 基因ID
- 1394, 12921, 58959
- NCBI登录号
- NP_004373
- 途径
- Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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