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小鼠 anti-人 IgE Antibody

FACS, EIA Monoclonal 4H10 IgG1 unconjugated
产品编号 ABIN238370
发货至: 中国
  • 抗原 See all IgE products
    IgE
    适用
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    宿主
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    小鼠
    克隆类型
    • 66
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    单克隆
    应用范围
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    Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Precipitation methods and Ion exchange chromatography
    免疫原
    Purified human IgE.
    克隆位点
    4H10
    亚型
    IgG1
  • 应用备注
    Suitable for Flow Cytometry and ELISA.

    Other applications not tested.
    Otimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    TBS with 15 mM sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • 抗原
    IgE
    Abstract
    IgE 产品
    背景
    Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.Synonyms: Immunoglobulin E human
    分子量
    180 kDa
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