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HLAG 抗体 (C-Term)

HLAG 适用: 人 WB, IHC (fro), IHC (p), IF 宿主: 小鼠 Monoclonal 2A12 unconjugated
产品编号 ABIN238366
发货至: 中国
  • 抗原 See all HLAG 抗体
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    抗原表位
    • 18
    • 15
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    C-Term
    适用
    • 121
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    • 1
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    宿主
    • 65
    • 62
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    小鼠
    克隆类型
    • 69
    • 63
    单克隆
    标记
    • 50
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    This HLAG antibody is un-conjugated
    应用范围
    • 85
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    • 43
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    The antibody 2A12 allows to discriminate between soluble HLA-G protein yielded by shedding from membrane-bound HLA-G forms that do not contain the intron 4-encoded epitope and soluble HLA-G5/HLA-G6 produced from intron 4-retaining alternatively spliced mRNAs. HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells.
    交叉反应 (详细)
    Species reactivity (tested):Human
    产品特性
    Synonyms: HLA-6.0, HLAG, MHC class I antigen G, HLA class I histocompatibility antigen
    纯化方法
    Purified by protein A
    免疫原
    C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupledto ovalbumin.
    克隆位点
    2A12
    亚型
    IgG1
    Top Product
    Discover our top product HLAG Primary Antibody
  • 应用备注
    Flow Cytometry: excellent for intracellular stainingWestern Blotting. Immunohistochemistry (paraffin and frozen sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 with 15 mM sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    别名
    HLA Class I alpha G / HLA-G (HLAG 产品)
    别名
    MHC-G antibody, B-F antibody, B-F-S04 antibody, B-F-S05 antibody, B-F-S06 antibody, B-F-S07 antibody, B-FI antibody, B-FIV antibody, BF2 antibody, BFa2 antibody, BFw-03 antibody, BFw-05 antibody, BFz-01 antibody, major histocompatibility complex, class I, G antibody, MHC BF1 class I antibody, HLA-G antibody, BF1 antibody
    背景
    HLA G belongs to the HLA class I heavy chain paralogues. It is a heterodimer consisting of a heavy chain (with a1, a2, a3 domains) and a light chain (beta 2 microglobulin). Alternate splicing provides both soluble and membrane bound forms of HLA G, with two soluble isoforms and four membrane bound isoforms. HLA G may be part of the fetal protection system and is expressed on fetal derived placental cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.0, HLAG, MHC class I antigen G
    基因ID
    3135
    UniProt
    P17693
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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