TSPAN12 抗体 (AA 1-100)
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- 抗原 See all TSPAN12 抗体
- TSPAN12 (Tetraspanin 12 (TSPAN12))
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抗原表位
- AA 1-100
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSPAN12 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TSPAN12
- 亚型
- IgG
- Top Product
- Discover our top product TSPAN12 Primary Antibody
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anti-Tetraspanin 12 (TSPAN12) (AA 111-224) antibody
TSPAN12 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) antibodyTSPAN12 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 111-224) antibodyTSPAN12 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 185-234) antibodyTSPAN12 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 豚鼠, 马, Bat, 猴, Pig WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 232-259), (C-Term) antibodyTSPAN12 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22652 unconjugated
anti-Tetraspanin 12 (TSPAN12) antibodyTSPAN12 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 179-228) antibodyTSPAN12 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TSPAN12 (Tetraspanin 12 (TSPAN12))
- 别名
- TSPAN12 (TSPAN12 产品)
- 别名
- tm4sf12 antibody, zgc:63880 antibody, EVR5 antibody, NET-2 antibody, NET2 antibody, TM4SF12 antibody, 9030619E17 antibody, AI426782 antibody, AI663988 antibody, AW111457 antibody, Tm4sf12 antibody, tetraspanin-7 antibody, tetraspanin 12 antibody, LOC412465 antibody, TSPAN12 antibody, tspan12 antibody, Tspan12 antibody
- 背景
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Synonyms: EVR5, NET2, NET-2, TM4SF12, Tetraspanin-12, Tspan-12, Tetraspan NET-2, Transmembrane 4 superfamily member 12, TSPAN12, UNQ774/PRO1568
Background: Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity.
- 基因ID
- 23554
- UniProt
- O95859
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