CHL1 抗体 (Cell Adhesion Molecule with Homology To L1CAM (Close Homolog of L1)) (AA 1-1080)

Details for Product anti-CHL1 Antibody No. ABIN1995815, 供应商: Log in to see
抗原
  • CALL
  • L1CAM2
  • A530023M13Rik
  • AI465420
  • LICAM2
  • cell adhesion molecule L1-like
  • cell adhesion molecule with homology to L1CAM
  • CHL1
  • Chl1
抗原表位
AA 1-1080
3
2
2
2
2
1
适用

14
4
1
宿主
小鼠
11
4
1
克隆类型 (克隆位点)
单克隆 ()
标记
This CHL1 antibody is un-conjugated
1
应用范围
ELISA, ELISA (Detection)
9
7
1
1
1
1
Supplier
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免疫原 Recombinant Human CHL-1 Protein (ABIN2215346)
克隆位点 6E6E4
亚型 IgG1
特异性 Human CHL-1
No cross-reactivity with Human cell lysate (293 cell line) in WB and ELISA.
无交叉反应
产品特性 This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CHL-1 (rhCHL-1, ABIN2215346 NP_006605.2, Met 1-Gln 1080,. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方法 purified by Protein A affinity chromatography
过滤 0.2 μm filtered
别名 CHL1 (CHL1 Antibody 摘要)
背景 Neural cell adhesion molecule L1-like protein, also known as Cell adhesion molecule with homology to L1CAM, Close homolog of L1, Chl1-like protein, Chl1 and Call, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and L1 / neurofascin / NgCAM family. CHL1 / CALL is expressed in the brain, in the cerebellum and in the spinal cord. It is detected in the retina and the optic nerve. It is also expressed in neurons and glial cells in the central nervous system and by schwann cells in the peripheral nervous system. CHL1 / CALL is an extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. CHL1 / CALL plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. CHL1 / CALL may play a role in regulating cell migration in nerve regeneration and cortical development.
NCBI登录号 NP_006605.2
应用备注 ELISA: 1-2 μg/mL
This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect CHL1-His. The detection limit for CHL1-His is approximately 0.078 ng/well.
ELISA(Det): 0.1-1 μg/mL
限制 仅限研究用
状态 Liquid
缓冲液 0.2 μm filtered solution in PBS with 5 % trehalose
储存液 Without preservative
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 4 °C,-20 °C,-80 °C
储存方法 This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
有效期 12 months