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Cytokeratin 18 抗体 (pSer33)

KRT18 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197077
发货至: 中国
  • 抗原 See all Cytokeratin 18 (KRT18) 抗体
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    抗原表位
    • 25
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    • 8
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    • 1
    pSer33
    适用
    • 251
    • 151
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    宿主
    • 164
    • 122
    • 3
    • 1
    • 1
    克隆类型
    • 151
    • 140
    多克隆
    标记
    • 143
    • 26
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    • 9
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    This Cytokeratin 18 antibody is un-conjugated
    应用范围
    • 216
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    • 27
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Keratin 18 antibody detects endogenous levels of Keratin 18 only when phosphorylated at serine 33.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from human Keratin 18 around the phosphorylation site of serine 33 (A-A-SP-V-Y).
    Top Product
    Discover our top product KRT18 Primary Antibody
  • 应用备注
    Immunohistochemistry: 1: 50approx. 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
    别名
    Cytokeratin 18 (KRT18 产品)
    别名
    CK18 antibody, K18 antibody, Krt1-18 antibody, CYK18 antibody, DreK18 antibody, cb83 antibody, dapk1 antibody, sb:cb83 antibody, wu:fa13f02 antibody, wu:fb36b04 antibody, krt18 antibody, MGC64569 antibody, MGC75922 antibody, KRT18 antibody, CK-18-A antibody, K18-A antibody, NC-11 antibody, cyk18 antibody, k18 antibody, krt18-a antibody, krt18-b antibody, krt18a antibody, xkendob antibody, keratin 18 antibody, keratin 18, type I L homeolog antibody, keratin 18, type I antibody, keratin, type I cytoskeletal 18 antibody, K18, simple type I keratin antibody, Keratin, type I cytoskeletal 18 antibody, keratin 18, type I S homeolog antibody, Krt18 antibody, KRT18 antibody, krt18 antibody, krt18.L antibody, LOC700569 antibody, LOC100136778 antibody, k1c18 antibody, LOC100008885 antibody, krt18.S antibody
    背景
    Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
    基因ID
    3875
    NCBI登录号
    NP_000215
    UniProt
    P05783
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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