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PRKDC 抗体 (pThr2609)

PRKDC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN196899
发货至: 中国
  • 抗原 See all PRKDC 抗体
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    抗原表位
    • 26
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    pThr2609
    适用
    • 162
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    宿主
    • 154
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    克隆类型
    • 149
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    多克隆
    标记
    • 96
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    This PRKDC antibody is un-conjugated
    应用范围
    • 85
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    Western Blotting (WB)
    特异性
    DNA PKcs (phospho-Thr2609) antibody detects endogenous levels of DNA PKcs only when phosphorylated at threonine 2609.
    纯化方法
    Immunoaffinity chromatography using epitope-specific phosphopeptide.
    免疫原
    The antiserum was produced against synthesized phosphopeptide derived from human DNA PKcs around the phosphorylation site of threonine 2609 (V-E-TP-Q-A).
    Top Product
    Discover our top product PRKDC Primary Antibody
  • 应用备注
    Suitable for use in Suitable for use in Western blot (1: 500-1: 1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    别名
    DNA-PKcs / PRKDC / XRCC7 (PRKDC 产品)
    别名
    DNA-PKcs antibody, DNAPK antibody, DNPK1 antibody, HYRC antibody, HYRC1 antibody, XRCC7 antibody, p350 antibody, DNA-PKCS antibody, dna-pkcs antibody, dnapk antibody, dnpk1 antibody, hyrc antibody, hyrc1 antibody, prkdc-A antibody, xrcc7 antibody, PRKDC antibody, AI326420 antibody, AU019811 antibody, DNAPDcs antibody, DOXNPH antibody, dxnph antibody, p460 antibody, scid antibody, slip antibody, protein kinase, DNA-activated, catalytic polypeptide antibody, protein kinase, DNA-activated, catalytic polypeptide L homeolog antibody, DNA-dependent protein kinase catalytic subunit antibody, protein kinase, DNA activated, catalytic polypeptide antibody, PRKDC antibody, prkdc.L antibody, LOC100633457 antibody, Prkdc antibody
    背景
    DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.Synonyms: DNA-dependent protein kinase catalytic subunit, DNPK1, HYRC, HYRC1, p460
    基因ID
    5591
    NCBI登录号
    NP_001075109
    UniProt
    P78527
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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