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PRR5L 抗体 (Center)

PRR5L 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887660
发货至: 中国
  • 抗原 See all PRR5L 抗体
    PRR5L (Proline Rich 5 Like (PRR5L))
    抗原表位
    • 1
    • 1
    • 1
    Center
    适用
    人, 小鼠
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 4
    This PRR5L antibody is un-conjugated
    应用范围
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    17 amino acid peptide near the center of human PRR5L.
    Top Product
    Discover our top product PRR5L Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    PRR5L (Proline Rich 5 Like (PRR5L))
    别名
    PRR5L (PRR5L 产品)
    别名
    PROTOR2 antibody, 2600010E01Rik antibody, 4833411O04Rik antibody, Protor-2 antibody, Protor2 antibody, RGD1309969 antibody, PRR5L antibody, FLJ14213 antibody, proline rich 5 like antibody, PRR5L antibody, Prr5l antibody, prr5l antibody
    背景
    Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2).PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2.Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
    Synonyms: Proline-rich protein 5-like, Protor-2, PROTOR2
    NCBI登录号
    NP_001153639
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