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AGT 抗体 (N-Term)

AGT 适用: 人 WB 宿主: 小鼠 Monoclonal 656CT5-8-4 unconjugated
产品编号 ABIN1882205
发货至: 中国
  • 抗原 See all AGT 抗体
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    抗原表位
    • 16
    • 15
    • 12
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 37-65, N-Term
    适用
    • 115
    • 51
    • 50
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 103
    • 35
    • 1
    小鼠
    克隆类型
    • 96
    • 43
    单克隆
    标记
    • 70
    • 18
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This AGT antibody is un-conjugated
    应用范围
    • 108
    • 46
    • 34
    • 27
    • 27
    • 20
    • 14
    • 14
    • 10
    • 9
    • 8
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This AGT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human AGT.
    克隆位点
    656CT5-8-4
    亚型
    IgG1
    Top Product
    Discover our top product AGT Primary Antibody
  • 应用备注
    WB: 1:100~1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Desong Liu, Fang Lu, Songhui Zhai, Liu Wei, Shi Ma, Xiuying Chen, Liqun Dong, Yannan Guo, Jin Wu, Zheng Wang: "Renin-angiotensin system gene polymorphisms in children with Henoch-Schönlein purpura in West China." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 11, Issue 4, pp. 248-55, (2010) (PubMed).

    Kieć-Wilk, Olszanecka, Mikołajczyk, Kawecka-Jaszcz et al.: "[Role of the M235T (c.704c>T) polymorphism of angiotensynogen gene as well as A724A (c.2171G>A) polymorphism of SERCA2a gene in ethiopathogenesis of left ventricular hypertrophy in essential..." in: Przegla̧d lekarski, Vol. 67, Issue 3, pp. 151-6, (2010) (PubMed).

    Procopciuc, Sitar-Tăut, Pop, Sitar-Tăut, Olteanu, Zdrenghea: "Renin angiotensin system polymorphisms in patients with metabolic syndrome (MetS)." in: European journal of internal medicine, Vol. 21, Issue 5, pp. 414-8, (2010) (PubMed).

  • 抗原
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    别名
    AGT (AGT 产品)
    别名
    ANHU antibody, SERPINA8 antibody, AI265500 antibody, AngI antibody, AngII antibody, Aogen antibody, Serpina8 antibody, ANRT antibody, Ang antibody, PAT antibody, wu:fb62f06 antibody, wu:fj87b02 antibody, zgc:111892 antibody, AGT antibody, angt antibody, ANGT antibody, angiotensinogen antibody, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody, AGT antibody, Agt antibody, agt antibody
    背景
    The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
    分子量
    53154
    NCBI登录号
    NP_000020
    UniProt
    P01019
    途径
    JAK/STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
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