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Src 抗体 (N-Term)

Src 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB41141 unconjugated
产品编号 ABIN1881833
发货至: 中国
  • 抗原 See all Src 抗体
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    抗原表位
    • 28
    • 25
    • 24
    • 21
    • 19
    • 18
    • 14
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-52, N-Term
    适用
    • 230
    • 144
    • 121
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 243
    • 19
    • 1
    克隆类型
    • 221
    • 42
    多克隆
    标记
    • 123
    • 22
    • 19
    • 17
    • 13
    • 12
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    This Src antibody is un-conjugated
    应用范围
    • 197
    • 139
    • 68
    • 55
    • 53
    • 34
    • 29
    • 29
    • 23
    • 12
    • 9
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    预测反应
    M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human SRC.
    克隆位点
    RB41141
    亚型
    IgG
    Top Product
    Discover our top product Src Primary Antibody
  • 应用备注
    IF: 1:50. IF: 1:50. WB: 1:2000. IHC-P: 1:50. IHC-P: 1:50. FC: 1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: "Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner." in: Cell stem cell, Vol. 7, Issue 4, pp. 496-507, (2010) (PubMed).

    Pradhan, Alrehani, Patel, Khatlani, Vijayan: "Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29059-68, (2010) (PubMed).

    Dergai, Tsyba, Dergai, Zlatskii, Skrypkina, Kovalenko, Rynditch: "Microexon-based regulation of ITSN1 and Src SH3 domains specificity relies on introduction of charged amino acids into the interaction interface." in: Biochemical and biophysical research communications, Vol. 399, Issue 2, pp. 307-12, (2010) (PubMed).

    Liu, Qiu, Li, Chen, Cao et al.: "Human phosphatidylethanolamine-binding protein 4 promotes transactivation of estrogen receptor alpha (ERalpha) in human cancer cells by inhibiting proteasome-dependent ERalpha degradation via ..." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 21934-42, (2010) (PubMed).

    Pene-Dumitrescu, Smithgall: "Expression of a Src family kinase in chronic myelogenous leukemia cells induces resistance to imatinib in a kinase-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21446-57, (2010) (PubMed).

  • 抗原
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    别名
    SRC (Src 产品)
    别名
    AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody
    物质类
    Viral Protein
    背景
    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    分子量
    59835
    NCBI登录号
    NP_005408, NP_938033
    UniProt
    P12931
    途径
    JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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