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SMAD1 抗体 (N-Term)

SMAD1 适用: 人 WB 宿主: 兔 Polyclonal RB33720 unconjugated
产品编号 ABIN1881815
发货至: 中国
  • 抗原 See all SMAD1 抗体
    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
    抗原表位
    • 23
    • 20
    • 18
    • 15
    • 14
    • 12
    • 10
    • 10
    • 8
    • 6
    • 6
    • 5
    • 5
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 206
    • 129
    • 94
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    宿主
    • 206
    • 16
    克隆类型
    • 196
    • 27
    多克隆
    标记
    • 104
    • 20
    • 13
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    This SMAD1 antibody is un-conjugated
    应用范围
    • 176
    • 91
    • 53
    • 52
    • 44
    • 32
    • 25
    • 19
    • 12
    • 11
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B, Zf, M, Rat, C
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SMAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SMAD1.
    克隆位点
    RB33720
    亚型
    Ig Fraction
    Top Product
    Discover our top product SMAD1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Ye, Yu, Hu, Lu, Xie: "Alterations of dendritic cell subsets in the peripheral circulation of patients with cervical carcinoma." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 78, (2010) (PubMed).

    Yang, Li, Al-Lamki, Southwood, Zhao, Lever, Grimminger, Schermuly, Morrell: "Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo." in: Circulation research, Vol. 107, Issue 2, pp. 252-62, (2010) (PubMed).

    Smythies, Shen, Bimczok, Novak, Clements, Eckhoff, Bouchard, George, Hu, Dandekar, Smith: "Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19593-604, (2010) (PubMed).

    Abhishek, Kumar, Arif, Patra, Choudhary, Sohail: "Induced expression of bone morphogenetic protein-6 and Smads signaling in human monocytes derived dendritic cells during sickle-cell pathology with orthopedic complications." in: Biochemical and biophysical research communications, Vol. 396, Issue 4, pp. 950-5, (2010) (PubMed).

  • 抗原
    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
    别名
    SMAD1 (SMAD1 产品)
    别名
    MLP antibody, Xmad1 antibody, Xsmad1 antibody, bsp1 antibody, jv4-1 antibody, jv41 antibody, madh1 antibody, madr1 antibody, smad-1 antibody, MADH1 antibody, fb39h09 antibody, wu:fb39h09 antibody, wu:fb97e04 antibody, 2/23 antibody, CG12399 antibody, Dmel\\CG12399 antibody, E(zen)2 antibody, En(vvl) antibody, MAD antibody, Mat antibody, P-Mad antibody, P-mad antibody, PMad antibody, Smad antibody, Smad1 antibody, apg antibody, c28 antibody, dMAD antibody, dMad antibody, l(2)K00237 antibody, l(2)k00237 antibody, mad antibody, p-Mad antibody, pMAD antibody, pMad antibody, pSmad antibody, BSP-1 antibody, BSP1 antibody, JV4-1 antibody, JV41 antibody, MADR1 antibody, AI528653 antibody, Madh1 antibody, Madr1 antibody, Mlp1 antibody, MusMLP antibody, smad1 antibody, xmad antibody, SMAD family member 1 antibody, Mothers against dpp antibody, SMAD family member 1 L homeolog antibody, smad1 antibody, SMAD1 antibody, Mad antibody, Smad1 antibody, smad1.L antibody
    背景
    The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
    分子量
    52260
    NCBI登录号
    NP_001003688, NP_005891
    UniProt
    Q15797
    途径
    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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