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DYRK1A 抗体 (C-Term)

DYRK1A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB40563 unconjugated
产品编号 ABIN1881275
发货至: 中国
  • 抗原 See all DYRK1A 抗体
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    抗原表位
    • 15
    • 14
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 718-745, C-Term
    适用
    • 76
    • 30
    • 22
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 70
    • 4
    • 3
    • 1
    克隆类型
    • 74
    • 4
    多克隆
    标记
    • 37
    • 7
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DYRK1A antibody is un-conjugated
    应用范围
    • 78
    • 48
    • 13
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Dyrk1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-745 amino acids from the C-terminal region of mouse Dyrk1a.
    克隆位点
    RB40563
    亚型
    Ig Fraction
    Top Product
    Discover our top product DYRK1A Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Park, Oh, Yoo, Jung, Song, Lee, Seo, Chung: "Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31895-906, (2010) (PubMed).

    Kurabayashi, Hirota, Sakai, Sanada, Fukada: "DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping." in: Molecular and cellular biology, Vol. 30, Issue 7, pp. 1757-68, (2010) (PubMed).

    Guo, Williams, Schug, Li: "DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 13223-32, (2010) (PubMed).

    Lee, Ha, Kim, Kim, Chang, Song, Kim: "Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33343-51, (2009) (PubMed).

  • 抗原
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    别名
    Dyrk1a (DYRK1A 产品)
    别名
    DYRK1A antibody, dyrk antibody, dyrk1 antibody, hp86 antibody, mnb antibody, mnbh antibody, DYRK antibody, DYRK1 antibody, HP86 antibody, MNB antibody, MNBH antibody, MRD7 antibody, 2310043O08Rik antibody, D16Ertd272e antibody, D16Ertd493e antibody, Dyrk antibody, ENSMUSG00000074897 antibody, Gm10783 antibody, Mnbh antibody, Mp86 antibody, mmb antibody, PSK47 antibody, dual specificity tyrosine phosphorylation regulated kinase 1A antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog antibody, DYRK1A antibody, dyrk1a antibody, Dyrk1a antibody, dyrk1a.S antibody
    背景
    Dyrk1a may play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.
    分子量
    85494
    NCBI登录号
    NP_001106860, NP_031916
    UniProt
    Q61214
    途径
    Mitotic G1-G1/S Phases
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