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BAD 抗体 (pSer57)

BAD 适用: 人 DB 宿主: 兔 Polyclonal RB39407 unconjugated
产品编号 ABIN1881101
发货至: 中国
  • 抗原 See all BAD 抗体
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    抗原表位
    • 34
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    • 15
    • 11
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    • 1
    • 1
    • 1
    pSer57
    适用
    • 383
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    • 2
    • 1
    • 1
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    • 1
    宿主
    • 459
    • 15
    • 1
    克隆类型
    • 441
    • 34
    多克隆
    标记
    • 180
    • 43
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    • 33
    • 11
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    • 1
    This BAD antibody is un-conjugated
    应用范围
    • 258
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    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S57 of human BAD.
    克隆位点
    RB39407
    亚型
    Ig Fraction
    Top Product
    Discover our top product BAD Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Galmiche, Ezzoukhry, François, Louandre, Sabbagh, Nguyen-Khac, Descamps, Trouillet, Godin, Regimbeau, Joly, Barbare, Duverlie, Mazière, Chatelain: "BAD, a proapoptotic member of the BCL2 family, is a potential therapeutic target in hepatocellular carcinoma." in: Molecular cancer research : MCR, Vol. 8, Issue 8, pp. 1116-25, (2010) (PubMed).

    Yu, Sun, Shen, Gao, Fan, Sun: "Expression of the apoptosis-related genes BCL-2 and BAD in human breast carcinoma and their associated relationship with chemosensitivity." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 107, (2010) (PubMed).

  • 抗原
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    别名
    BAD (BAD 产品)
    别名
    bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
    背景
    The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
    分子量
    18392
    NCBI登录号
    NP_004313, NP_116784
    UniProt
    Q92934
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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