TNFRSF18 抗体 (C-Term)
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北京 101111
Quick Overview for TNFRSF18 抗体 (C-Term) (ABIN184156)
抗原
See all TNFRSF18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LRSQCMWPRE TQLLLEVPPS TEDARSCQFP EEERGERSAE EKGRLGDLWV
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against TNFRSF18. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 241 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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别名
- TNFRSF18
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背景
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The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Alias Symbols: AITR, GITR, CD357, GITR-D
Protein Interaction Partner: LNX1, TRAF3, TRAF2, TRAF1, TNFSF18, TNFRSF18,
Protein Size: 241 -
分子量
- 26 kDa
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基因ID
- 8784
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NCBI登录号
- NM_004195, NP_004186
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UniProt
- Q9Y5U5
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途径
- Cancer Immune Checkpoints
抗原
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