TNFRSF18 抗体 (C-Term)
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- 抗原 See all TNFRSF18 抗体
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF18 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LRSQCMWPRE TQLLLEVPPS TEDARSCQFP EEERGERSAE EKGRLGDLWV
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TNFRSF18. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human TNFRSF18
- Top Product
- Discover our top product TNFRSF18 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 241 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- 别名
- TNFRSF18 (TNFRSF18 产品)
- 别名
- GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
- 背景
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The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Alias Symbols: AITR, GITR, CD357, GITR-D
Protein Interaction Partner: LNX1, TRAF3, TRAF2, TRAF1, TNFSF18, TNFRSF18,
Protein Size: 241 - 分子量
- 26 kDa
- 基因ID
- 8784
- NCBI登录号
- NM_004195, NP_004186
- UniProt
- Q9Y5U5
- 途径
- Cancer Immune Checkpoints
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