PRKRA 抗体 (Middle Region)
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北京 101111
Quick Overview for PRKRA 抗体 (Middle Region) (ABIN183963)
抗原
See all PRKRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA KRNAAEKFLA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against PRKRA. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PRKRA
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 313 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Interaction between PKR and PACT mediated by LPS-inducible NF-?B in human gingival cells." in: Journal of cellular biochemistry, Vol. 113, Issue 1, pp. 165-73, (2011) (PubMed).
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- PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))
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别名
- PRKRA
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背景
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PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA).
Alias Symbols: RAX, PACT, DYT16, HSD14
Protein Interaction Partner: ZMAT3, PRKRA, TARBP2, LYAR, STAU1, UBC, H1F0, EIF2AK2, CCDC124, C1orf35, DDX50, NOC3L, NOP16, STAU2, ZNF346, GTPBP4, DICER1, RBM34, EBNA1BP2, IFRD2, TCOF1, BMI1, SRPK3, POLR2G, MDC1, CAND1, UBE2I, SIRT7, ZFP28, KIAA1377, NKRF, SNX5, RABEPK, CEBPZ, SHC1, Z
Protein Size: 313 -
分子量
- 34 kDa
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基因ID
- 8575
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NCBI登录号
- NM_003690, NP_003681
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UniProt
- O75569
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途径
- Regulatory RNA Pathways
抗原
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