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SNRNP70 抗体 (N-Term)

SNRNP70 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN183913
发货至: 中国
  • 抗原 See all SNRNP70 抗体
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 23
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 兔, 马
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This SNRNP70 antibody is un-conjugated
    应用范围
    • 23
    • 14
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SNRP70
    Top Product
    Discover our top product SNRNP70 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 437 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Mueller, Hertel, Cambi: "G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4059-71, (2011) (PubMed).

    Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

  • 抗原
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    别名
    SNRP70 (SNRNP70 产品)
    别名
    rnpu1z antibody, rpu1 antibody, snrp70 antibody, u170k antibody, u1ap antibody, u1rnp antibody, SNRP70 antibody, wu:fc20b04 antibody, zgc:136450 antibody, 2700022N21Rik antibody, 3200002N22Rik antibody, 70kDa antibody, AI325098 antibody, R74807 antibody, Rnulp70 antibody, Snrp70 antibody, Srnp70 antibody, U1-70 antibody, U1-70K antibody, RNPU1Z antibody, RPU1 antibody, Snp1 antibody, U170K antibody, U1AP antibody, U1RNP antibody, small nuclear ribonucleoprotein, U1 70kDa subunit antibody, small nuclear ribonucleoprotein U1 subunit 70 antibody, small nuclear ribonucleoprotein 70 (U1) antibody, small nuclear ribonucleoprotein, U1 70kDa subunit L homeolog antibody, snrnp70 antibody, SNRNP70 antibody, Snrnp70 antibody, snrnp70.L antibody
    背景
    SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    Alias Symbols: RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K
    Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
    Protein Size: 437
    分子量
    52 kDa
    基因ID
    6625
    NCBI登录号
    NM_003089, NP_003080
    UniProt
    P08621
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