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AATF 抗体 (N-Term)

The 兔 多克隆 anti-AATF antibody is suitable to detect AATF in samples from 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow 和 Pig. It has been validated for WB.
产品编号 ABIN183737
发货至: 中国
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Quick Overview for AATF 抗体 (N-Term) (ABIN183737)

抗原

See all AATF 抗体
AATF (Apoptosis Antagonizing Transcription Factor (AATF))

适用

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人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, Pig

宿主

  • 55
  • 4
  • 1

克隆类型

  • 54
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多克隆

标记

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This AATF antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MAGPQPLALQ LEQLLNPRPS EADPEADPEE ATAARVIDRF DEGEDGEGDF

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against AATF. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human AATF
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 560 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    AATF (Apoptosis Antagonizing Transcription Factor (AATF))

    别名

    AATF

    背景

    The AATF is a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
    Alias Symbols: DED, CHE1, CHE-1
    Protein Interaction Partner: MDM2, DAPK3, AR, HIPK2, NGDN, UBC, TSG101, LIN28A, MMS19, ZNF468, NEDD4L, WHSC1, SMAD3, EFNB3, CPD, UBD, CAND1, PIN1, SIRT7, SUMO2, CHEK2, RELA, tat, MAGED1, PCBD2, SS18L1, LZTR1, MPHOSPH6, POLR2J, MPP6, PAWR, DAZAP2, ATR, ATM, CHEK1, LDOC1, SP1, RB1, MAP
    Protein Size: 560

    分子量

    63 kDa

    基因ID

    26574

    NCBI登录号

    NM_012138, NP_036270

    UniProt

    Q9NY61

    途径

    Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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