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TADA3L 抗体 (C-Term)

TADA3 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN183710
发货至: 中国
  • 抗原 See all TADA3L (TADA3) 抗体
    TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
    抗原表位
    • 15
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 49
    • 10
    • 10
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼
    宿主
    • 47
    • 2
    克隆类型
    • 48
    • 1
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TADA3L antibody is un-conjugated
    应用范围
    • 36
    • 23
    • 11
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    RVRMADNEVM DAFRKIMAAR QKKRTPTKKE KDQAWKTLKE RESILKLLDG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against TADA3L. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human TADA3L
    Top Product
    Discover our top product TADA3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 432 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
    别名
    TADA3L (TADA3 产品)
    别名
    ADA3 antibody, NGG1 antibody, STAF54 antibody, TADA3L antibody, hADA3 antibody, Tada3l antibody, 1110004B19Rik antibody, AI987856 antibody, fa03f04 antibody, tada3 antibody, wu:fa03f04 antibody, zgc:63596 antibody, ada3 antibody, ada3-A antibody, ngg1 antibody, tada3l antibody, tada3l-a antibody, ada3-B antibody, tada3l-B antibody, transcriptional adaptor 3 antibody, transcriptional adapter 3 pseudogene antibody, transcriptional adaptor 3 (NGG1 homolog, yeast)-like antibody, transcriptional adaptor 3 L homeolog antibody, transcriptional adaptor 3 S homeolog antibody, TADA3 antibody, Tada3 antibody, LOC732883 antibody, LOC100061462 antibody, tada3 antibody, LOC100619707 antibody, tada3l antibody, tada3.L antibody, tada3.S antibody
    背景
    Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
    Alias Symbols: ADA3, NGG1, hADA3, TADA3L
    Protein Interaction Partner: HEXIM2, CCDC101, CCNC, TP53, USP22, KDM1A, TADA2A, KAT2B, TAF5L, NUP205, SUPT3H, YEATS2, MBIP, WDR5, MAP3K7, DR1, PIAS4, MAGEH1, ING5, XRCC6, SUMO2, SREBF1, TXNRD2, NR1I2, RARA, ESR1, AR, KAT2A, EP300, CTNNB1, ANKRD12, ATXN7, TAF10, FAM107B, ADPGK, HSPA8,
    Protein Size: 432
    分子量
    49 kDa
    基因ID
    10474
    NCBI登录号
    NM_006354, NP_006345
    UniProt
    O75528
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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