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ZFP36 抗体 (N-Term)

ZFP36 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN183636
发货至: 中国
  • 抗原 See all ZFP36 抗体
    ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
    抗原表位
    • 8
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 46
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 4
    克隆类型
    • 42
    • 4
    多克隆
    标记
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZFP36 antibody is un-conjugated
    应用范围
    • 34
    • 20
    • 9
    • 5
    • 5
    • 5
    • 1
    • 1
    Western Blotting (WB)
    序列
    MDLTAIYESL LSLSPDVPVP SDHGGTESSP GWGSSGPWSL SPSDSSPSGV
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against ZFP36. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ZFP36
    Top Product
    Discover our top product ZFP36 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 326 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
    别名
    ZFP36 (ZFP36 产品)
    别名
    G0S24 antibody, GOS24 antibody, NUP475 antibody, RNF162A antibody, TIS11 antibody, TTP antibody, zfp-36 antibody, c3h-1 antibody, g0s24 antibody, gos24 antibody, nup475 antibody, rnf162a antibody, tis11 antibody, ttp antibody, ZFP36 antibody, C3H-1 antibody, Gos24 antibody, Nup475 antibody, TIS11D antibody, TISII antibody, Tis11 antibody, Ttp antibody, Zfp-36 antibody, ZFP36 ring finger protein antibody, ZFP36 ring finger protein L homeolog antibody, tristetraproline antibody, Tristetraproline antibody, similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth antibody, zinc finger protein 36 antibody, ZFP36 antibody, zfp36.L antibody, EDI_287240 antibody, Bm1_42085 antibody, LOAG_03119 antibody, zfp36 antibody, Zfp36 antibody
    背景
    ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
    Alias Symbols: TTP, G0S24, GOS24, TIS11, NUP475, zfp-36, RNF162A
    Protein Interaction Partner: YWHAB, PPP2CA, DNAJB1, DCP1B, DHX36, PRR5L, XRN1, UBC, TRAF2, EXOSC6, UPF2, EXOSC8, YWHAQ, TNF, DCP2, EDC3, DCP1A, EDC4, CDK6, APP, LIN28A, SH3KBP1, PABPC1, NCL, MAP3K4, HSPA4, HDAC7, HDAC3, NFKB1, HOXC9, HDAC1, CCDC85B, MAPKAPK2, YWHAG, SFN, HMGB1, NUP21
    Protein Size: 326
    分子量
    34 kDa
    基因ID
    7538
    NCBI登录号
    NM_003407, NP_003398
    UniProt
    P26651
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