ZFP36 抗体 (N-Term)
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- 抗原 See all ZFP36 抗体
- ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZFP36 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MDLTAIYESL LSLSPDVPVP SDHGGTESSP GWGSSGPWSL SPSDSSPSGV
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ZFP36. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZFP36
- Top Product
- Discover our top product ZFP36 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 326 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
- 别名
- ZFP36 (ZFP36 产品)
- 别名
- G0S24 antibody, GOS24 antibody, NUP475 antibody, RNF162A antibody, TIS11 antibody, TTP antibody, zfp-36 antibody, c3h-1 antibody, g0s24 antibody, gos24 antibody, nup475 antibody, rnf162a antibody, tis11 antibody, ttp antibody, ZFP36 antibody, C3H-1 antibody, Gos24 antibody, Nup475 antibody, TIS11D antibody, TISII antibody, Tis11 antibody, Ttp antibody, Zfp-36 antibody, ZFP36 ring finger protein antibody, ZFP36 ring finger protein L homeolog antibody, tristetraproline antibody, Tristetraproline antibody, similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth antibody, zinc finger protein 36 antibody, ZFP36 antibody, zfp36.L antibody, EDI_287240 antibody, Bm1_42085 antibody, LOAG_03119 antibody, zfp36 antibody, Zfp36 antibody
- 背景
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ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
Alias Symbols: TTP, G0S24, GOS24, TIS11, NUP475, zfp-36, RNF162A
Protein Interaction Partner: YWHAB, PPP2CA, DNAJB1, DCP1B, DHX36, PRR5L, XRN1, UBC, TRAF2, EXOSC6, UPF2, EXOSC8, YWHAQ, TNF, DCP2, EDC3, DCP1A, EDC4, CDK6, APP, LIN28A, SH3KBP1, PABPC1, NCL, MAP3K4, HSPA4, HDAC7, HDAC3, NFKB1, HOXC9, HDAC1, CCDC85B, MAPKAPK2, YWHAG, SFN, HMGB1, NUP21
Protein Size: 326 - 分子量
- 34 kDa
- 基因ID
- 7538
- NCBI登录号
- NM_003407, NP_003398
- UniProt
- P26651
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