ID4 抗体 (N-Term)
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- 抗原 See all ID4 抗体
- ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Pig, 犬, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ID4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MKAVSPVRPS GRKAPSGCGG GELALRCLAE HGHSLGGSAA AAAAAAAARC
- 预测反应
- Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against ID4. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ID4
- Top Product
- Discover our top product ID4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 161 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability." in: Carcinogenesis, Vol. 32, Issue 4, pp. 636-42, (2011) (PubMed).
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LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability." in: Carcinogenesis, Vol. 32, Issue 4, pp. 636-42, (2011) (PubMed).
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- 抗原
- ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))
- 别名
- ID4 (ID4 产品)
- 别名
- Idb4 antibody, bHLHb27 antibody, cb547 antibody, fb77d04 antibody, sb:cb547 antibody, wu:fb77d04 antibody, zgc:123214 antibody, bhlhb27 antibody, id4 antibody, id4a antibody, idb4 antibody, IDB4 antibody, inhibitor of DNA binding 4 antibody, inhibitor of DNA binding 4, HLH protein antibody, inhibitor of DNA binding 4, HLH protein S homeolog antibody, Id4 antibody, id4 antibody, id4.S antibody, ID4 antibody
- 背景
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Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995).[supplied by OMIM].
Alias Symbols: IDB4, bHLHb27
Protein Interaction Partner: TCF3, TCF4, ID3, MYOD1, HES1,
Protein Size: 161 - 分子量
- 17 kDa
- 基因ID
- 3400
- NCBI登录号
- NM_001546, NP_001537
- UniProt
- P47928
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