CHRNB2 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for CHRNB2 抗体 (Middle Region) (ABIN183541)
抗原
See all CHRNB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- KIEVKHFPFD QQNCTMKFRS WTYDRTEIDL VLKSEVASLD DFTPSGEWDI
-
预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Yeast: 77%
-
产品特性
- This is a rabbit polyclonal antibody against CHRNB2. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CHRNB2
-
-
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 26-233) antibody
CHRNB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2D12A2 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 86-244) antibodyCHRNB2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 322-458) antibodyCHRNB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (Internal Region) antibodyVerified CHRNB2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 26-130) antibodyCHRNB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 21-70) antibodyCHRNB2 适用: 人, 大鼠, 小鼠, 犬, Cow, Pig, 豚鼠, 斑马鱼, Bat, 猴, 非洲爪蟾, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 155-204) antibodyCHRNB2 适用: 人, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 96-107), (Extracellular) antibody (Atto 594)CHRNB2 适用: 大鼠 IHC, IF, IC, LCI 宿主: 兔 Polyclonal Atto 594
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 66-100) antibodyCHRNB2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB53583 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) antibodyCHRNB2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 502 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))
-
别名
- CHRNB2
-
背景
-
Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
Alias Symbols: EFNL3, nAChRB2
Protein Interaction Partner: CRELD2, CHRNA4, CHRNA2,
Protein Size: 502 -
分子量
- 57 kDa
-
基因ID
- 1141
-
NCBI登录号
- NM_000748, NP_000739
-
UniProt
- P17787
-
途径
- Sensory Perception of Sound, Feeding Behaviour
抗原
-
