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MED17 抗体 (N-Term)

MED17 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN182953
发货至: 中国
  • 抗原 See all MED17 抗体
    MED17 (Mediator Complex Subunit 17 (MED17))
    抗原表位
    • 16
    • 9
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 52
    • 26
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马
    宿主
    • 52
    • 3
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED17 antibody is un-conjugated
    应用范围
    • 49
    • 31
    • 14
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
    序列
    AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6
    Top Product
    Discover our top product MED17 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 651 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MED17 (Mediator Complex Subunit 17 (MED17))
    别名
    CRSP6 (MED17 产品)
    别名
    crsp6 antibody, CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, TRAP80 antibody, 77kDa antibody, C330002H14Rik antibody, Crsp6 antibody, Trap80 antibody, mediator of RNA polymerase II transcription subunit 17 antibody, mediator complex subunit 17 antibody, mediator complex subunit 17 L homeolog antibody, AOR_1_2446154 antibody, VDBG_01663 antibody, med17 antibody, med17.L antibody, MED17 antibody, Med17 antibody
    背景
    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
    Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
    Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
    Protein Size: 651
    分子量
    73 kDa
    基因ID
    9440
    NCBI登录号
    NM_004268, NP_004259
    UniProt
    Q9NVC6
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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