Prohibitin 抗体 (C-Term)
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- 抗原 See all Prohibitin (PHB) 抗体
- Prohibitin (PHB)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 斑马鱼, 兔, Cow, 豚鼠, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Prohibitin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AEQQKKAAII SAEGDSKAAE LIANSLATAG DGLIELRKLE AAEDIAYQLS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against PHB. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PHB
- Top Product
- Discover our top product PHB Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 272 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Prohibitin (PHB)
- 别名
- PHB (PHB 产品)
- 别名
- phb1 antibody, MGC75944 antibody, PHB antibody, Phb antibody, ACYPI000080 antibody, phb antibody, PHB1 antibody, Bap32 antibody, sr:nyz128 antibody, wu:fa18f07 antibody, wu:fb09f05 antibody, prohibitin1 antibody, xphb1 antibody, prohibitin antibody, prohibitin-2 antibody, prohibitin L homeolog antibody, PHB antibody, phb antibody, LOC484431 antibody, LOC5576054 antibody, Phb antibody, phb.L antibody
- 背景
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Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Alias Symbols: PHB1
Protein Interaction Partner: FUS, HUWE1, SUMO2, SPRTN, STAU1, MDM2, SUZ12, EED, RNF2, PARP1, NAP1L1, COX6C, LONRF3, FBXO6, ADRB2, HDAC5, RAF1, KRAS, RAPH1, IPO11, SMG5, YWHAZ, YWHAB, VDAC2, RPS4X, RPL7, PRKCD, PLEC, NPM1, LMNA, IGHG1, HSP90AB1, GTF3C1, DBN1, COL9A2, CAPZA1, SLC25A5,
Protein Size: 272 - 分子量
- 30 kDa
- 基因ID
- 5245
- NCBI登录号
- NM_002634, NP_002625
- UniProt
- P35232
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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