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Prohibitin 抗体 (C-Term)

PHB 适用: 人, 小鼠, 大鼠, 斑马鱼, 兔, Cow, 豚鼠, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN182681
发货至: 中国
  • 抗原 See all Prohibitin (PHB) 抗体
    Prohibitin (PHB)
    抗原表位
    • 16
    • 13
    • 12
    • 12
    • 9
    • 9
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 137
    • 62
    • 60
    • 11
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 斑马鱼, 兔, Cow, 豚鼠, 犬, 马
    宿主
    • 116
    • 21
    克隆类型
    • 105
    • 32
    多克隆
    标记
    • 70
    • 12
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Prohibitin antibody is un-conjugated
    应用范围
    • 105
    • 51
    • 46
    • 27
    • 22
    • 22
    • 14
    • 13
    • 11
    • 9
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    AEQQKKAAII SAEGDSKAAE LIANSLATAG DGLIELRKLE AAEDIAYQLS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against PHB. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human PHB
    Top Product
    Discover our top product PHB Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 272 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Prohibitin (PHB)
    别名
    PHB (PHB 产品)
    别名
    phb1 antibody, MGC75944 antibody, PHB antibody, Phb antibody, ACYPI000080 antibody, phb antibody, PHB1 antibody, Bap32 antibody, sr:nyz128 antibody, wu:fa18f07 antibody, wu:fb09f05 antibody, prohibitin1 antibody, xphb1 antibody, prohibitin antibody, prohibitin-2 antibody, prohibitin L homeolog antibody, PHB antibody, phb antibody, LOC484431 antibody, LOC5576054 antibody, Phb antibody, phb.L antibody
    背景
    Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
    Alias Symbols: PHB1
    Protein Interaction Partner: FUS, HUWE1, SUMO2, SPRTN, STAU1, MDM2, SUZ12, EED, RNF2, PARP1, NAP1L1, COX6C, LONRF3, FBXO6, ADRB2, HDAC5, RAF1, KRAS, RAPH1, IPO11, SMG5, YWHAZ, YWHAB, VDAC2, RPS4X, RPL7, PRKCD, PLEC, NPM1, LMNA, IGHG1, HSP90AB1, GTF3C1, DBN1, COL9A2, CAPZA1, SLC25A5,
    Protein Size: 272
    分子量
    30 kDa
    基因ID
    5245
    NCBI登录号
    NM_002634, NP_002625
    UniProt
    P35232
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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