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PSMD4/ASF 抗体 (C-Term)

The 兔 多克隆 anti-PSMD4/ASF antibody is suitable to detect PSMD4/ASF in samples from 人, 小鼠, 大鼠, Cow, 绵羊, 兔, 犬, 豚鼠, 马 和 Pig. It has been validated for WB 和 IHC.
产品编号 ABIN182537
发货至: 中国
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Quick Overview for PSMD4/ASF 抗体 (C-Term) (ABIN182537)

抗原

See all PSMD4/ASF (Psmd4) 抗体
PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

适用

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人, 小鼠, 大鼠, Cow, 绵羊, 兔, 犬, 豚鼠, 马, Pig

宿主

  • 63
  • 6
  • 1

克隆类型

  • 53
  • 17
多克隆

标记

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This PSMD4/ASF antibody is un-conjugated

应用范围

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  • 9
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    VMQDPEFLQS VLENLPGVDP NNEAIRNAMG SLASQATKDG KKDKKEEDKK

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against PSMD4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 377 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

    别名

    PSMD4

    背景

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid.
    Alias Symbols: AF, ASF, S5A, AF-1, MCB1, Rpn10, pUB-R5
    Protein Interaction Partner: UBC, cdc20, XPC, SPRTN, PSMD14, MDM2, PSMC2, PSMA1, ADRM1, UBQLN1, TXNL1, PSMD3, PSMD2, PSMD1, PSMC6, PSMC4, PSMC1, UCHL5, RPS12, PSMD8, UBQLN4, VCP, GJA1, DIO2, SCHIP1, FBXO6, PARK2, UL76, FBXO25, LOC100044627, Gm4705, LOC677113, Rps6-ps4, Rpl34-ps1, Rpl
    Protein Size: 377

    分子量

    41 kDa

    基因ID

    5710

    NCBI登录号

    NM_002810, NP_002801

    UniProt

    P55036

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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