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NFKB2 抗体 (C-Term)

NFKB2 适用: 人, 大鼠, Cow, Pig, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN182483
发货至: 中国
  • 抗原 See all NFKB2 抗体
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    抗原表位
    • 16
    • 14
    • 13
    • 13
    • 11
    • 11
    • 6
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    • 4
    • 4
    • 3
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term
    适用
    • 136
    • 96
    • 60
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, Cow, Pig, 兔, 马
    宿主
    • 135
    • 7
    克隆类型
    • 124
    • 17
    • 1
    多克隆
    标记
    • 80
    • 12
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFKB2 antibody is un-conjugated
    应用范围
    • 87
    • 48
    • 41
    • 28
    • 22
    • 17
    • 16
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    SDSDSDSEGP EKDTRSSFRG HTPLDLTCST LVKTLLLNAA QNTMEPPL
    预测反应
    Cow: 77%, Horse: 85%, Human: 100%, Pig: 77%, Rabbit: 92%, Rat: 77%
    产品特性
    This is a rabbit polyclonal antibody against NFKB2. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human NFKB2
    Top Product
    Discover our top product NFKB2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 933 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Yang, Li, Gong: "Characterization of a negative feedback network between SUMO4 expression and NFkappaB transcriptional activity." in: Biochemical and biophysical research communications, Vol. 381, Issue 4, pp. 477-81, (2009) (PubMed).

    Volger, Fledderus, Kisters, Fontijn, Moerland, Kuiper, van Berkel, Bijnens, Daemen, Pannekoek, Horrevoets: "Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis." in: The American journal of pathology, Vol. 171, Issue 1, pp. 326-37, (2007) (PubMed).

  • 抗原
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    别名
    NFKB2 (NFKB2 产品)
    别名
    NF-kappaB2 antibody, lyt antibody, p49 antibody, p49/p100 antibody, p50B antibody, p52 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antibody, Nfkb2 antibody
    背景
    NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
    Alias Symbols: p52, H2TF1, LYT10, LYT-10
    Protein Interaction Partner: FBXW11, UBC, RELB, RELA, REL, NFKB1, CHUK, BCL3, SUMO1, NEDD8, TNFAIP3, BIRC2, EPS8, VCP, UBD, BRRF1, COMMD1, COMMD2, MAP3K14, BTRC, NFKB2, FBXW7, TSG101, IKBKG, SUMO2, DPF2, PSMD11, NFKBIZ, TNIP2, HDAC5, NFKBIB, HDAC4, USP2, NFKBIE, RPL6, IKBKB, TSC22D3,
    Protein Size: 900
    分子量
    97 kDa
    基因ID
    4791
    NCBI登录号
    NM_002502, NP_002493
    UniProt
    Q00653
    途径
    Toll-Like Receptors Cascades
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