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SNF8 抗体 (N-Term)

SNF8 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN182378
发货至: 中国
  • 抗原 See all SNF8 抗体
    SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
    抗原表位
    • 15
    • 11
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 40
    • 26
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼
    宿主
    • 52
    • 2
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 22
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNF8 antibody is un-conjugated
    应用范围
    • 28
    • 22
    • 13
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MHRRGVGAGA IAKKKLAEAK YKERGTVLAE DQLAQMSKQL DMFKTNLEEF
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against SNF8. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human EAP30
    Top Product
    Discover our top product SNF8 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 258 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
    别名
    EAP30 (SNF8 产品)
    别名
    d11moh34 antibody, vps22 antibody, Dot3 antibody, EAP30 antibody, VPS22 antibody, D11moh34 antibody, RGD1310144 antibody, D11Moh34 antibody, D11MOH34 antibody, zgc:101578 antibody, SNF8, ESCRT-II complex subunit antibody, eap30 subunit of ell complex, putative antibody, EAP30 subunit of ELL complex antibody, SNF8, ESCRT-II complex subunit S homeolog antibody, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) antibody, snf8 antibody, TA17290 antibody, TVAG_107410 antibody, Bm1_05145 antibody, SNF8 antibody, Snf8 antibody, snf8.S antibody
    背景
    ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM].
    Alias Symbols: Dot3, EAP30, VPS22
    Protein Interaction Partner: GOLGA2, VPS25, TRIM54, VAC14, UBC, BCAT1, SUV39H2, ACBD3, DUS3L, WDR12, PRMT6, RPUSD2, KDM1A, EFTUD2, TTC1, HARS, GTF2F1, GTF2E1, ELL, RBP1, MCM2, ADORA1, METTL14, NUDCD3, RILP, VPS36, CHMP6, VPS28, SNF8, TSG101, VPS20, NIF3L1, DVL2,
    Protein Size: 258
    分子量
    29 kDa
    基因ID
    11267
    NCBI登录号
    NM_007241, NP_009172
    UniProt
    Q96H20
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