Macrophage Mannose Receptor 1 抗体
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- 抗原 See all Macrophage Mannose Receptor 1 (MRC1) 抗体
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Macrophage Mannose Receptor 1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
- 特异性
- This antibody recognises the Mannose Receptor, a 175 kDa type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands.
- 纯化方法
- Affinity Chromatography on Protein G
- 免疫原
- Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line.
- 克隆位点
- MR5D3
- 亚型
- IgG2a
- Top Product
- Discover our top product MRC1 Primary Antibody
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anti-Mannose Receptor, C Type 1 (MRC1) (AA 22-130) antibody
MRC1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro), Func 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibody (PE)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 PE
anti-Mannose Receptor, C Type 1 (MRC1) (AA 201-300) antibodyMRC1 适用: 人, 小鼠, 大鼠, 犬 FACS, WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) (Internal Region) antibodyMRC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibody (FITC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 FITC
anti-Mannose Receptor, C Type 1 (MRC1) antibody (APC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 APC
anti-Mannose Receptor, C Type 1 (MRC1) (AA 225-492) antibodyMRC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL0387 unconjugated
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- 应用备注
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Western Blot. Immunoprecipitation. Immunohistochemistry on frozen sections. Flow Cytometry: 1/10 - 1/20, Use 10 μL of the suggested working dilution to label 10^6 cell in 100 μL, CD206 is expressed weakly at the cell surface. Staining may be increased following membrane permeabilisation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- 别名
- CD206 / MRC1 (MRC1 产品)
- 别名
- CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
- 背景
- CD206 is a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites. The expression of CD206 is not restricted to macrophages, but is also present on immature dendritic cells (DCs), endothelial cells, kidney mesangial cells, retinal pigment epithelium and tracheal smooth muscle cells.Synonyms: C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CLEC13D, CLEC13DL, MRC1L1, Macrophage mannose receptor, Macrophage mannose receptor 1-like protein 1
- 基因ID
- 17533
- NCBI登录号
- NP_032651
- UniProt
- Q61830
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