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CCL24 抗体

CCL24 适用: 人 WB, EIA, Func 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN181600
发货至: 中国
  • 抗原 See all CCL24 抗体
    CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
    适用
    • 34
    • 32
    • 8
    宿主
    • 50
    • 13
    • 7
    • 1
    山羊
    克隆类型
    • 62
    • 7
    多克隆
    标记
    • 28
    • 16
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCL24 antibody is un-conjugated
    应用范围
    • 42
    • 26
    • 17
    • 13
    • 13
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody detects Eotaxin-2.
    纯化方法
    Immunoaffinity Chromatography employing an immobilized Human Eotaxin-2 matrix
    免疫原
    Highly pure (> 98%) E.coli derived recombinant Human Eotaxin-2.
    Top Product
    Discover our top product CCL24 Primary Antibody
  • 应用备注
    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofEotaxin-2 (100 ng/mL), a concentration of 4.0 - 6.0 μg/mL is required. ELISA: Indirect: To detect Eotaxin-2 by indirect ELISA (using 100 μL/well antibody solution)a concentration of 0.5 - 2.0 μg/mL is required. In conjunction with compatible secondaryreagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant Eotaxin-2. Sandwich: To detect hEotaxin-2 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL is required. In conjunction with Biotinylated Anti-HumanEotaxin-2 as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well of
    限制
    仅限研究用
  • 溶解方式
    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
    别名
    Eotaxin-2 / CCL24 (CCL24 产品)
    别名
    Ckb-6 antibody, MPIF-2 antibody, MPIF2 antibody, SCYA24 antibody, CKb-6 antibody, Scya24 antibody, C-C motif chemokine ligand 24 antibody, chemokine (C-C motif) ligand 24 antibody, CCL24 antibody, Ccl24 antibody
    背景
    Eotaxin 2 is a member of the CC chemokine family, based on the presence of the CC motif and homology with other known CC chemokines. Eotaxin 2 cDNA encodes a 119 amino acid residue precursor protein with a 26 amino acid residue signal peptide that is cleaved to generate a mature protein predicted to contain 93 amino acid residues with an N glycosylation site. Mature human eotaxin 2 has a predicted molecular mass of approximately 10.6 kDa. Compared to other CC chemokines, eotaxin 2 exhibits 40 %, 42 %, and 39 % amino acid identity to MCP3, MIP1 alpha, and eotaxin, respectively. Human CC chemokine eotaxin 2 maps to chromosome 7q11.23. Both eotaxin and eotaxin 2 activate and attract eosinophils and basophils. A receptor for human eotaxin has been identified and found to be the third numbered receptor in the C-C chemokine subfamily of receptors (CCR3. On eosinophils, the effects of eotaxin 2 is inhibited by an CCR3 antibody and cross-desensitized by eotaxin and MCP4, suggesting that all three CC chemokines act through CCR3. Eotaxin 2 mRNA is weakly expressed in activated monocytes and T lymphocytes. Recombinant eotaxin 2 induces chemotaxis of eosinophils, basophils, and resting T lymphocytes but not monocytes and activated T lymphocytes. Eotaxin 2 inhibits colony formation in myleloid progenitor cells.Synonyms: C-C motif chemokine 24, CK-beta-6, Eosinophil chemotactic protein 2, MPIF-2, MPIF2, Myeloid progenitor inhibitory factor 2, SCYA24, Small-inducible cytokine A24
    基因ID
    6369
    NCBI登录号
    NP_002982
    UniProt
    O00175
    途径
    Regulation of Actin Filament Polymerization
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