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Podoplanin 抗体

PDPN 适用: 人 WB, FACS, IP, IHC (p), IHC (fro) 宿主: 大鼠 Monoclonal NZ-1 unconjugated
产品编号 ABIN180856
发货至: 中国
  • 抗原 See all Podoplanin (PDPN) 抗体
    Podoplanin (PDPN)
    适用
    • 82
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    宿主
    • 56
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    大鼠
    克隆类型
    • 52
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    单克隆
    标记
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    This Podoplanin antibody is un-conjugated
    应用范围
    • 73
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The monoclonal antibody will detect Human Podoplanin on the surface of lymphatic endothelial cells and kidney podocytes. Therefore, it will be a useful tool to study lymphatic vessel density in and around Human tumors. Does not react with Mouse.
    产品特性
    Synonyms: Glycoprotein 36, PA2.26 antigen, T1-alpha, Aggrus, PDPN, GP36, PSEC0003, PSEC0025
    纯化方法
    Purified
    克隆位点
    NZ-1
    亚型
    IgG2a
    Top Product
    Discover our top product PDPN Primary Antibody
  • 应用备注
    FACS (1/200). Western blot (>/= 1/200). Immunoprecipitation: 1/50. Immunostaining/Immunohistochemistry on Frozen and Paraffin Sections (1/200). Suitablefor Formalin-Fixed Paraffin Embedded Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in working aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • Martín-Villar, Fernández-Muñoz, Parsons, Yurrita, Megías, Pérez-Gómez, Jones, Quintanilla: "Podoplanin associates with CD44 to promote directional cell migration." in: Molecular biology of the cell, Vol. 21, Issue 24, pp. 4387-99, (2011) (PubMed).

  • 抗原
    Podoplanin (PDPN)
    别名
    Podoplanin (PDPN 产品)
    别名
    PDPN antibody, AGGRUS antibody, GP36 antibody, GP40 antibody, Gp38 antibody, HT1A-1 antibody, OTS8 antibody, PA2.26 antibody, T1A antibody, T1A-2 antibody, OTS-8 antibody, RANDAM-2 antibody, T1-alpha antibody, T1a antibody, T1alpha antibody, E11 antibody, RTI40 antibody, podoplanin antibody, PDPN antibody, Pdpn antibody
    背景
    Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a Mr 38,000 membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha
    基因ID
    10630
    UniProt
    Q86YL7
    途径
    Dicarboxylic Acid Transport
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