Podoplanin 抗体 (PDPN)

Details for Product anti-PDPN Antibody No. ABIN180856, 供应商: Log in to see
抗原
  • PDPN
  • AGGRUS
  • GP36
  • GP40
  • Gp38
  • HT1A-1
  • OTS8
  • PA2.26
  • T1A
  • T1A-2
  • OTS-8
  • RANDAM-2
  • T1-alpha
  • T1a
  • T1alpha
  • E11
  • RTI40
  • podoplanin
  • podoplanin-like
  • PDPN
  • Pdpn
  • LOC100738269
适用

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克隆类型 (克隆位点)
单克隆 ()
标记
This Podoplanin antibody is un-conjugated
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应用范围
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
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选项
Supplier
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Supplier Product No.
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克隆位点 NZ-1
亚型 IgG2a
特异性 The monoclonal antibody will detect Human Podoplanin on the surface of lymphatic endothelial cells and kidney podocytes. Therefore, it will be a useful tool to study lymphatic vessel density in and around Human tumors. Does not react with Mouse.
产品特性 Synonyms: Glycoprotein 36, PA2.26 antigen, T1-alpha, Aggrus, PDPN, GP36, PSEC0003, PSEC0025
纯化方法 Purified
别名 Podoplanin (PDPN Antibody 摘要)
背景 Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a Mr 38,000 membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.Synonyms: Aggrus, GP36, Glycoprotein 36, PA2.26 antigen, PDPN, PSEC0003, PSEC0025, T1-alpha
基因ID 10630
UniProt Q86YL7
途径 Dicarboxylic Acid Transport
应用备注 FACS (1/200). Western blot (>/= 1/200). Immunoprecipitation: 1/50. Immunostaining/Immunohistochemistry on Frozen and Paraffin Sections (1/200). Suitablefor Formalin-Fixed Paraffin Embedded Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
状态 Liquid
浓度 0.5 mg/mL
缓冲液 PBS, 0.09 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in working aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
有效期 12 months
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Podoplanin (PDPN) antibody (ABIN180856) anti-Podoplanin (PDPN) antibody
有引用在: Martín-Villar, Fernández-Muñoz, Parsons, Yurrita, Megías, Pérez-Gómez, Jones, Quintanilla: "Podoplanin associates with CD44 to promote directional cell migration." in: Molecular biology of the cell, Vol. 21, Issue 24, pp. 4387-99, 2010 (PubMed).

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