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BCL2L1 抗体 (BCL2-Like 1) (AA 35-50)

Details for Product anti-BCL2L1 Antibody No. ABIN180627, 供应商: Log in to see
抗原
  • bcl-XL
  • bcl-x
  • bcl-x(l)
  • bcl-xl/s
  • bcl-xs
  • bcl2l
  • bclx
  • bclxl
  • xR11
  • BCL2L1
  • Bcl-xS
  • BCL-XL/S
  • BCL2L
  • BCLX
  • BCLXL
  • BCLXS
  • Bcl-X
  • PPP1R52
  • bcl-xL
  • bcl-xS
  • Bcl(X)L
  • Bcl-XL
  • Bcl-Xs
  • Bcl2l
  • BclX
  • Bcl-xl
  • Bclx
  • bcl-X
  • BCL-XL
  • Bcl-xL
  • bcl-xl
  • BCL2-like 1
  • transgene insertion 2, Craig B Thompson
  • Bcl2-like 1
  • bcl2l1
  • BCL2L1
  • LOC100224900
  • Tg(BCL2L1)2Cbt
  • Bcl2l1
Alternatives
anti-小鼠 BCL2L1 抗体 for Cytometry by Time of Flight
抗原表位
AA 35-50
151
37
28
26
19
15
15
12
11
10
10
9
9
7
6
6
6
5
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
人, 小鼠
474
354
318
151
37
22
17
15
15
13
13
10
4
4
2
2
1
宿主
小鼠
287
222
3
3
克隆类型 (克隆位点)
单克隆 ()
标记
This BCL2L1 antibody is un-conjugated
26
17
11
9
7
7
6
6
5
5
5
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
1
1
1
1
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
398
199
169
157
155
149
127
94
93
27
10
8
7
7
3
3
2
2
1
Supplier
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免疫原 A synthetic peptide corresponding to aa 35-50 of mouse BclxL protein. AA Sequence: TEAPEETEAERETPSARemarks: Mol. Wt. of Antigen: 27 kDaEpitope: aa 35-50
克隆位点 7D8
亚型 IgG2a
特异性 This antibody detects Bcl-XL.
产品特性 Synonyms: Bcl2-L-1, BCL2L1, BCL2L, BCLX, Bcl-x, bcl-xL, bcl-xS, Bcl-2-like protein 1
纯化方法 Protein A chromatography
别名 Bcl-2-Like 1 (BCL2L1 Antibody 摘要)
背景 Bcl-X has two isoforms, Bcl-XL (long) a 241 amino acid protein and Bcl-XS (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl-2 family. Bcl-XL represses cell death, while Bcl-XS favors cell death.Synonyms: BCL2L, BCL2L1, BCLX, Bcl-2-like protein 1, Bcl-x, Bcl2-L-1, bcl-xL, bcl-xS
UniProt Q07817
研究领域 Cancer
途径 Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
应用备注 Flow Cytometry. Immunofluorescence. Immunohistology (Formalin/paraffin): 1: 400 for 30 min at RT, staining of formalin-fixedtissues REQUIRES boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minfollowed by cooling at RT for 20 min. Positive Control: Hodgkin's lymphoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
浓度 0.2 mg/mL
缓冲液 10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.
有效期 12 months
厂商提供的图像
Immunohistochemistry (IHC) image for anti-BCL2L1 抗体 (BCL2-Like 1) (AA 35-50) (ABIN180627) anti-BCL2-Like 1 (BCL2L1) (AA 35-50) antibody
背景 Hsu, Youle: "Nonionic detergents induce dimerization among members of the Bcl-2 family." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13829-34, 1997 (PubMed).

Hsu, Wolter, Youle: "Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 8, pp. 3668-72, 1997 (PubMed).

Wolter, Hsu, Smith, Nechushtan, Xi, Youle: "Movement of Bax from the cytosol to mitochondria during apoptosis." in: The Journal of cell biology, Vol. 139, Issue 5, pp. 1281-92, 1997 (PubMed).