Botulinum Neurotoxin Type B (BoNT/B) 抗体
BoNT/B
适用: Clostridium botulinum
cELISA, FACS
宿主: 小鼠
Monoclonal
GR-3G7
unconjugated
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- 抗原 See all Botulinum Neurotoxin Type B (BoNT/B) 抗体
- Botulinum Neurotoxin Type B (BoNT/B)
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适用
- Clostridium botulinum
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Cell-ELISA (cELISA), Flow Cytometry (FACS)
- 特异性
- Anti-BoNT/B
- 纯化方法
- Protein G
- 免疫原
- genetic immunisation with cDNA encoding BoNT/B
- 克隆位点
- GR-3G7
- 亚型
- IgG1
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anti-Botulinum Neurotoxin Type B (BoNT/B) antibody
BoNT/B 适用: Clostridium botulinum ELISA, WB 宿主: Chicken egg unconjugated
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 限制
- 仅限研究用
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- 浓度
- 2 mg/mL
- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- 抗原
- Botulinum Neurotoxin Type B (BoNT/B)
- 别名
- BoNT B, Lightchain (BoNT/B 产品)
- 别名
- botulinum neurotoxin type B antibody, botulinum neurotoxin type B, BoNT/B antibody, boNT/B antibody, CLL_0038 antibody
- 物质类
- Bacteria
- 背景
- Botulinum neurotoxin type B (BoNT/B) is produced by Clostridium botulinum, a genetically diverse class of anaerobic, spore-forming, gram-positive bacilli. Seven different botulinum toxin groups have been identified serologically and are called botulinum toxin type A,B,C,D,E,F, and G. BoNT/B is a two-chain polypeptide with a 100-kDa heavy chain, which is responsible for neurospecific binding joined by a disulphide bond to a 50-kDa light chain, a zinc-endopeptidase which blocks neurotransmitter release. BoNT/B is one of the most poisonous naturally occurring substances. It inhibits acetylcholine release from neuromuscular junctions while it is used as an important therapeutic mainstay in the treatment of spasticity disorders and as a cosmetic treatment.
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